Sphingosine-1-phosphate | EDG receptor ligand

CAS:
26993-30-6
Catalog Number:
10-4526
Activity:
EDG receptor ligand
Chemical Name:
Sphingosine-1-phosphate, D-erythro
Molecular Weight:
379.47
Molecular Formula:
C18H38NO5P
Solubility:
Soluble in anhydrous methanol (up to 0.5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in methanol or in BSA/water may be stored at -20° for up to 2 months. Precipitate may form upon thawing, but will redissolve with warming.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
1 mg$65.00
5 mg$240.00

Sphingosine-1-phosphate (26993-30-6) is an endogenous sphingolipid metabolite known to be involved in many cellular responses including angiogenesis, vascular maturation, cardiac development and immunity. These effects are mediated through a family of 5 G-protein-coupled receptors.1,2,3

References/Citations:

1) Spiegel and Milstien (2003) Sphingosine-1-phosphate: an enigmatic signaling lipid; Nat. Rev. Mol. Cell Biol., 4 397
2) Rosen et al. (2009) Sphingosine-1-phosphate receptor signaling; Annu. Rev .Biochem., 78 743
3) Maceyka et al. (2012) Sphingosine-1-phosphate signaling and its role in disease; Trends Cell Biol., 22 50

CAS:
26993-30-6
Catalog Number:
10-4526
Activity:
EDG receptor ligand
Chemical Name:
Sphingosine-1-phosphate, D-erythro
Molecular Weight:
379.47
Molecular Formula:
C18H38NO5P
Solubility:
Soluble in anhydrous methanol (up to 0.5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in methanol or in BSA/water may be stored at -20° for up to 2 months. Precipitate may form upon thawing, but will redissolve with warming.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee