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  • Focus Biomolecules cell signaling reagent supplier, chemical structure AG-879 | NGFR kinase inhibitor | CAS 148741-30-4
    AG-879 (148741-30-4) inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 μM). No inhibition of EGF, or PDGF receptor phosphorylation is...

  • Focus Biomolecules cell signaling reagent supplier, structure of GW-441756 | NGFR kinase inhibitor | CAS 504433-23-2
    GW-441756 (504433-23-2) is a potent and selective TrkA kinase inhibitor (IC50 = 2 nM). References/Citations1) Wood et al. (2004) Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles...

  • Focus Biomolecules supplier, chemical structure of LM11A-31 | p75NTR ligand | Promotes neurogenesis | CAS 1243259-19-9
    LM11A-31 (CAS 1243259-19-9) is a nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-responsive cells.1 Promotes functional recovery in a mouse model of spinal...

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