my account
Login
  Loading... Please wait...

Product Details

GSK-3787 | PPAR delta antagonist

GSK-3787 (188591-46-0) is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor delta (PPARδ) plC50 = 6.6. It covalently binds to Cys 249 in the PPARδ binding site.

References/Citations
1) Shearer et al., (2010) Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist; J. Med. Chem., 53 1857
2) Palkar et al. (2010) Cellular and pharmacological selectivity of the peroxisone proliferator-activated receptorδ antagonist GSK3787; Mol. Pharmacol. 78 419

swipe
Focus Biomolecules cell signaling reagent supplier, structure of GSK-3787 | PPAR delta antagonist | CAS 188591-46-0

Catalog#  10-1001

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
188591-46-0
Catalog Number:
10-1001
Activity:
PPARδ antagonist
Chemical Name:
4-Chloro-N-(2-{[5-(trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide
Molecular Weight:
392.78
Molecular Formula:
C15H12ClF3N2O3S
Solubility:
Soluble in DMSO (up to 30 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the GSK-3787 | PPAR delta antagonist to your wish list.