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Bestatin HCl | Aminopeptidase inhibitor

CAS:
65391-42-6
Catalog Number:
10-1286
Activity:
Aminopeptidase inhibitor
Chemical Name:
[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine HCl
Molecular Weight:
344.84
Molecular Formula:
C16H24N2O4 HCl
Solubility:
Soluble in Water (up to 10 mg/ml). Also soluble in DMSO and Ethanol.
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Bestatin HCl (65391-42-6) inhibits leucine aminopeptidase and aminopeptidases B and N. Inhibits leukotriene A4 hydrolase. Displays immunostimulant activity via activation of macrophages and T lymphocytes. Displays antitumor activity.

References/Citations:

1) Orning et al. (1991), Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes; J. Biol. Chem., 266 1375
2) Wang et al. (2010), The effect of different species aminopeptidase N structure on the activity screening of aminopeptidase N inhibitor; Biol. Pharm. Bull., 33 1658

Bestatin HCl | Aminopeptidase inhibitor is also available in the Cellular Metabolism Library.
CAS:
65391-42-6
Catalog Number:
10-1286
Activity:
Aminopeptidase inhibitor
Chemical Name:
[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine HCl
Molecular Weight:
344.84
Molecular Formula:
C16H24N2O4 HCl
Solubility:
Soluble in Water (up to 10 mg/ml). Also soluble in DMSO and Ethanol.
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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