my account
Login
  Loading... Please wait...

COX

Sort by
  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Celecoxib | COX II inhibitor | CAS 169590-42-5
    $35.00
    Celecoxib (169590-42-5) is a selective inhibitor of cyclooxygenase-2 (COX-2) IC50 = 15 and 0.04 μM for COX-1 and COX-2 respectively.1 Potent and clinically useful antiinflammatory agent.2 Cancer chemopreventive...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of MK-886 | FLAP inhibitor | CAS 118414-82-1
    $70.00
    MK-886 (118414-82-7) is an inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM)2. MK-886 also inhibits PPARα (80% inhibition at 10...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Oxaprozin | NFkB inhibitor | CAS 21256-18-8
    $70.00
    Oxaprozin (21256-18-8) is a clinically useful non-steroidal anti-inflammatory drug.1 In addition to typical NSAID COX inhibition, oxaprozin may also exert anti-inflammatory effects via inhibition of the Akt/IKK/NF-κB...

  • Rofecoxib | Selective COX-2 inhibitor
    $60.00
    Rofecoxib (162011-90-7) is a potent and selective COX-2 inhibitor with 1000-fold selectivity over COX-1, IC50=26 nm vs >50 μM1. Potent nonsteroidal anti-inflammatory agent1. Rofecoxib is a clinically useful NSAID which...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Sulindac Sulfide | NFkB inhibitor | CAS 32004-67-4
    $50.00
    Sulindac sulfide (32004-67-4) is the active metabolite of cyclooxygenase inhibitor sulindac.1 Strongly inhibits Ras induced malignant transformation and Ras/Raf dependent transactivation.2 Sulindac sulfide induces apoptosis...

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus