Other Immunology
Showing 1–12 of 21 results
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New Products
AZD7762 | Checkpoint kinase 1/2 inhibitor
AZD7762 (860352-01-8, free base) is a potent and selective inhibitor of checkpoint kinases 1 and 2 (IC50 = 5 nM for both).1 It abrogates DNA damage...$60.00 – $200.00 Select options -
Aminopeptidases
Bestatin HCl | Aminopeptidase inhibitor
Bestatin HCl (65391-42-6) inhibits leucine aminopeptidase and aminopeptidases B and N. Inhibits leukotriene A4 hydrolase. Displays immunostimulant ...$40.00 – $100.00 Select options -
Immunology
Biotinyl tyramide | Signal amplification reagent for immunoassays
Biotinyl tyramide (41994-02-9) is a reagent for use in catalyzed reporter deposition (CARD) signal amplification protocols in a variety of immunoas...$40.00 – $110.00 Select options -
New Products
CID1067700 | Rab7 GTPase inhibitor
CID1067700 (314042-01-8) is a specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with...$65.00 – $240.00 Select options -
Immunology
Cycloheximide-N-ethylethanoate | FKBP12 inhibitor
FKBP12 inhibitor (IC50=4.4 µM) with neuroregenerative properties. Does not inhibit protein synthesis (as does cycloheximide).1 Mimics a helical pep...$65.00 – $260.00 Select options -
New Products
DO264 | ABHD12 inhibitor
DO264 (2301866-59-9) is a potent, reversible competitive inhibitor of ABHD12 (α/β-hydrolase domain-containing 12) which shows negligible interactio...$70.00 – $280.00 Select options -
Approved Drugs
FTY720 HCl | Sphingosine-1-phosphate receptor agonist
FTY720 HCl (162359-56-0) is an analog of sphingosine (Cat.# 10-2287) which, when taken up into cells, is phosphorylated and acts as an agonist at s...$45.00 – $170.00 Select options -
New Products
GKT-137831 | NADPH oxidase NOX1/4 inhibitor
GKT-137831 (1218942-37-0) is an NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immun...$70.00 – $280.00 Select options -
New Products
GSK8612 | Highly selective TBK1 inhibitor
GSK8612 (2361659-62-1) is a highly selective and potent (avg. pIC50 = 6.8 versus recombinant TBK1) inhibitor of Tank-binding Kinase-1 (TBK1) with h...$95.00 – $370.00 Select options -
Approved Drugs
Ingenol-3-angelate | PKC activator
Ingenol-3-angelate (75567-37-2) is a selective activator of protein kinase C which displays antileukemic activity mediated via PKCδ.1 In contrast, ...$110.00 – $430.00 Select options -
Cancer
IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent
IPI-549 (1693758-51-8) is a potent and highly selective inhibitor of PI3K-γ in both biochemical (IC50 = 16 nM) and cellular (IC50 = 12.2 nM) assays...$50.00 – $175.00 Select options -
Arthritis
Kenpaullone | GSK-3ß/CDK/KLF4 inhibitor
Kenpaullone (142273-20-9) inhibits GSK-3β (IC50=0.23 µM) as well as several cyclin-dependent kinases (CDKs), IC50=0.4, 0.68 and 0.85 µM for cdk1, c...$80.00 – $240.00 Select options
