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Infectious Diseases

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  • Apoptolidin | Apoptosis inducer
    Apoptolidin | Apoptosis inducer
    $248.00
    Apoptolidin (194874-06-1) is a powerful inducer of apoptosis in a variety of cancer cell lines.1 Is believed to act via inhibition of F0F1-ATPase2 but correlation studies indicate that a second mechanism may be the actual...

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  • Blasticidin S HCl | Antibiotic selection agent
    Blasticidin S HCl | Antibiotic selection agent
    $80.00
    Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1 Inhibits translation by trapping deformed tRNA on the ribosome.1 The ABC-type transporter NppA1A2BCD...

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  • Cilastatin Na | Protease inhibitor
    Cilastatin Na | Protease inhibitor
    $60.00
    Cilastatin Na (81129-83-1) is a dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4 to E4.1  Inhibits the mammalian β-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus...

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  • Cycloserine, D(+) | NMDA, glycine site partial agonist
    Cycloserine, D(+) | NMDA, glycine site partial agonist
    $60.00
    D-Cycloserine (68-41-7) is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors.1 Blocks kainate-induced seizures2 and displays anticonvulsant effects3 in rat models. D-Cycloserine facilitates...

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  • Daptomycin | Antibiotic
    Daptomycin | Antibiotic
    $44.00
    Daptomycin (103060-53-3) is a cyclic anionic lipopeptide calcium-dependent antibiotic1. Useful for the treatment of serious Gram-positive infections including antibiotic-resistant strains such as MRSA and VRE2...

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  • Dehydrozingerone | Glutathione sponge
    Dehydrozingerone | Glutathione sponge
    $35.00
    Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been...

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  • Divin | Divisome assembly inhibitor
    Divin | Divisome assembly inhibitor
    $75.00
    Divin is an iron, cobalt, and copper chelator that arrests the late stages of cytokinesis in bacteria by blocking the physical process of constriction in dividing cells without affecting FtsZ. Iron starvation leads to...

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  • Echinomycin | HIF-1alpha inhibitor
    Echinomycin | HIF-1alpha inhibitor
    $90.00
    Echinomycin is a potent and selective hypoxia inducible factor 1α (HIF-1α) inhibitor. It binds to DNA via bifunctional intercalation, blocking the interaction of HIF-1α.1 Protects mice against relapsed...

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  • Flavopiridol HCl | CDK inhibitor
    Flavopiridol HCl | CDK inhibitor
    $50.00
    Flavopiridol HCl (131740-09-5) is a cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase.1 Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells.2 Potentiates the effects...

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  • Hydroxychloroquine sulfate | 747-36-4 | Structure | Supplier
    Hydroxychloroquine sulfate | Autophagy inhibitor
    $60.00
    Hydroxychloroquine sulfate (747-36-4) is a lysosomotropic agent which inhibits autophagy and triggers apoptosis in a variety of cell types.1,2 Augments the anticancer activity of DNA-damaging chemotherapy...

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  • Minocycline HCl | Neuroprotective; antiapoptotic
    Minocycline HCl | Neuroprotective; antiapoptotic
    $38.00
    Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. Reduces MMP-9 activity2. Attenuates disease severity in mouse models of...

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  • Mupirocin | 12650-69-0 | Structure | Supplier
    Mupirocin | Antibiotic
    $80.00
    Mupirocin (12650-69-0) is a topical antibiotic/antibacterial.1 It inhibits isoleucyl-tRNA synthase. High level mupirocin resistance was found in 8.2% of Staphylococcus aureus and 15.6% of coagulase-negative staphylococci...

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  • Quinacrine HCl | Antiprotozoan / Anticancer
    Quinacrine HCl | Antiprotozoan / Anticancer
    $30.00
    Quinacrine HCl (69-05-6) is an antiprotozoan drug used for malaria and giardiasis and has recently been investigated in treating lupus, as an anticancer agent, inflammation, and as a female sterilization agent.1 It has been...

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  • Sulfasalazine | Anti-inflammatory / antibiotic
    Sulfasalazine | Anti-inflammatory / antibiotic
    $20.00
    Sulfasalazine (599-79-1) is an approved drug with diverse potential applications. Sulfasalzine is a clinically useful agent for the treatment of colitis and ileocolitis.1 It is metabolized by intestinal bacteria to release...

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