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Infectious Diseases

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  • Apoptolidin | Apoptosis inducer
    Apoptolidin | Apoptosis inducer
    $248.00
    Apoptolidin (194874-06-1) is a powerful inducer of apoptosis in a variety of cancer cell lines.1 Is believed to act via inhibition of F0F1-ATPase2 but correlation studies indicate that a second mechanism may be the actual...

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  • Blasticidin S HCl | Antibiotic selection agent
    Blasticidin S HCl | Antibiotic selection agent
    $80.00
    Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1 Inhibits translation by trapping deformed tRNA on the ribosome.1 The ABC-type transporter NppA1A2BCD...

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  • Cilastatin Na | Protease inhibitor
    Cilastatin Na | Protease inhibitor
    $60.00
    Cilastatin Na (81129-83-1) is a dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4 to E4.1  Inhibits the mammalian β-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus...

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  • Cycloserine, D(+) | NMDA, glycine site partial agonist
    Cycloserine, D(+) | NMDA, glycine site partial agonist
    $60.00
    D-Cycloserine (68-41-7) is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors.1 Blocks kainate-induced seizures2 and displays anticonvulsant effects3 in rat models. D-Cycloserine facilitates...

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  • Daptomycin | Antibiotic
    Daptomycin | Antibiotic
    $44.00
    Daptomycin (103060-53-3) is a cyclic anionic lipopeptide calcium-dependent antibiotic1. Useful for the treatment of serious Gram-positive infections including antibiotic-resistant strains such as MRSA and VRE2...

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  • Dehydrozingerone | Glutathione sponge
    Dehydrozingerone | Glutathione sponge
    $35.00
    Dehydrozingerone (1080-12-2) is a structural half analog of curcumin (Cat.# 10-1243) and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been...

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  • Echinomycin | HIF-1alpha inhibitor
    Echinomycin | HIF-1alpha inhibitor
    $90.00
    Echinomycin is a potent and selective hypoxia inducible factor 1α (HIF-1α) inhibitor. It binds to DNA via bifunctional intercalation, blocking the interaction of HIF-1α.1 Protects mice against relapsed...

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  • Flavopiridol HCl | CDK inhibitor
    Flavopiridol HCl | CDK inhibitor
    $50.00
    Flavopiridol HCl (131740-09-5) is a cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase.1 Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells.2 Potentiates the effects...

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  • Hydroxychloroquine sulfate | 747-36-4 | Structure | Supplier
    Hydroxychloroquine sulfate | Autophagy inhibitor
    $60.00
    Hydrochloroquine sulfate (747-36-4) is a lysosomotropic agent which inhibits autophagy and triggers apoptosis in a variety of cell types.1,2 Augments the anticancer activity of DNA-damaging chemotherapy...

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  • Minocycline HCl | Neuroprotective; antiapoptotic
    Minocycline HCl | Neuroprotective; antiapoptotic
    $38.00
    Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. Reduces MMP-9 activity2. Attenuates disease severity in mouse models of...

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  • Mupirocin | 12650-69-0 | Structure | Supplier
    Mupirocin | Antibiotic
    $80.00
    Mupirocin (12650-69-0) is a topical antibiotic/antibacterial.1 It inhibits isoleucyl-tRNA synthase. High level mupirocin resistance was found in 8.2% of Staphylococcus aureus and 15.6% of coagulase-negative staphylococci...

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  • Quinacrine HCl | Antiprotozoan / Anticancer
    Quinacrine HCl | Antiprotozoan / Anticancer
    $30.00
    Quinacrine HCl (69-05-6) is an antiprotozoan drug used for malaria and giardiasis and has recently been investigated in treating lupus, as an anticancer agent, inflammation, and as a female sterilization agent.1 It has been...

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  • Sulfasalazine | Anti-inflammatory / antibiotic
    Sulfasalazine | Anti-inflammatory / antibiotic
    $20.00
    Sulfasalazine (599-79-1) is an approved drug with diverse potential applications. Sulfasalzine is a clinically useful agent for the treatment of colitis and ileocolitis.1 It is metabolized by intestinal bacteria to release...

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