Inflammation
COX Glucocorticoid receptors Inflammasome Leukotrienes Lipoxygenase Nf-KB NMDA receptors PAF Prostanoid receptores ROS STING Other Inflammation
Showing 1–12 of 105 results
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Approved Drugs
Allopregnanolone | GABA-A positive allosteric modulator
Allopregnanolone (516-54-1) is an endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approve...$70.00 – $280.00 Select options -
Antioxidants
Ambroxol HCl | Free radical scavenger
Ambroxol HCl (18683-91-5) is a radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveol...$50.00 – $100.00 Select options -
Diabetes
Amlexanox | TBK1 inhibitor / Antidiabetic
Amlexanox (68302-57-8) improves obesity-related metabolic dysfunction in mouse models.1 Increases thermogenesis and weight loss, decreases steatosi...$40.00 – $100.00 Select options -
Cancer
Anacardic Acid | HAT inhibitor
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50’...$35.00 – $140.00 Select options -
Antivirals
Andrographolide | Induces mitochondrial -mediated apoptosis in lymphoma cells
Andrographolide (5508-58-7) is the major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-ap...$34.00 – $136.00 Select options -
Inflammation
AS-041164 | PI 3-Kgamma inhibitor
AS-041164 (6318-41-8) is a potent, ATP-competitive, and isoform-selective PI3-Kinase inhibitor (IC50 = 0.07, 0.24, 1.45, and 1.70 μM for the γ, α, ...$60.00 – $240.00 Select options -
Inflammation
AS-605240 | PI 3-Kinase inhibitor
AS-605240 (648450-29-7) is a potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ), IC50 = 8 nM displaying 30-fold selectivity over PI 3-Kδ and...$50.00 – $190.00 Select options -
Calcineurin
Ascomycin | FKBP ligand immunosuppressant
Ascomycin (11011-38-4) is an analog of FK-506 (Cat.# 10-1103). Potent immunosuppressant1. Binds to FKBP122 and inhibits calcineurin and NFAT. Ascom...$35.00 – $120.00 Select options -
Approved Drugs
Auranofin | IKK inhibitor
Auranofin (34031-32-8) is a disease-modifying antirheumatic drug (DMARD) , It is a potent inhibitor of selenoenzyme thioredoxin reductase and IκB k...$50.00 Select options -
Cellular Stress
Auraptene | Neuroprotective / Neuritogenic agent
Auraptene (495-02-3) is a bioactive terpenoid occurring in a variety of citrus fruits and possessing therapeutic potential.1 Displays neuritogeni...$30.00 – $98.00 Select options -
Apoptosis
Baicalein | Inhibitor of protein tyrosine kinase in leukemia (CEM cells)
Baicalein (491-67-8) is an inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis1. Originally repor...$40.00 – $148.00 Select options -
Antioxidants
Bakuchiol | Antioxidant
Bakuchiol (10309-37-2) is a natural terpenoid antioxidant.1 Inhibits oxidative stress-induced decrease in mitochondrial membrane potential and asso...$65.00 – $240.00 Select options
