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COX

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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Celecoxib | COX II inhibitor | CAS 169590-42-5
    $35.00
    Celecoxib (169590-42-5) is a selective inhibitor of cyclooxygenase-2 (COX-2) IC50 = 15 and 0.04 μM for COX-1 and COX-2 respectively.1 Potent and clinically useful antiinflammatory agent.2 Cancer chemopreventive...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Oxaprozin | NFkB inhibitor | CAS 21256-18-8
    $70.00
    Oxaprozin (21256-18-8) is a clinically useful non-steroidal anti-inflammatory drug.1 In addition to typical NSAID COX inhibition, oxaprozin may also exert anti-inflammatory effects via inhibition of the Akt/IKK/NF-κB...

  • Rofecoxib | Selective COX-2 inhibitor
    $60.00
    Rofecoxib (162011-90-7) is a potent and selective COX-2 inhibitor with 1000-fold selectivity over COX-1, IC50=26 nm vs >50 μM1. Potent nonsteroidal anti-inflammatory agent1. Rofecoxib is a clinically useful NSAID which...

  • SC-560 | Selective COX-1 inhibitor
    $50.00
    SC-560 (188817-13-2) is a highly selective (700-fold selective over COX-2) and potent (IC50 = 9 nM) inhibitor of cyclooxygenase-1(COX-1).1 SC-560 inhibited TNF α-induced PGE2 synthesis in neurons and, PGE2 and...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Sulindac Sulfide | NFkB inhibitor | CAS 32004-67-4
    $50.00
    Sulindac sulfide (32004-67-4) is the active metabolite of cyclooxygenase inhibitor sulindac.1 Strongly inhibits Ras induced malignant transformation and Ras/Raf dependent transactivation.2 Sulindac sulfide induces apoptosis...

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