Nf-KB
Showing 1–12 of 17 results
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Cancer
Anacardic Acid | HAT inhibitor
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50’...$35.00 – $140.00 Select options -
Antivirals
Andrographolide | Induces mitochondrial -mediated apoptosis in lymphoma cells
Andrographolide (5508-58-7) is the major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-ap...$34.00 – $136.00 Select options -
Cell adhesion
BAY 11-7082 | IKK inhibitor
BAY 11-7082 (19542-67-7) inhibits cytokine-induced IκB-α phosphorylation via inhibition of IκB Kinase which results in inhibition of NFκB 1. Inhibi...$60.00 – $200.00 Select options -
Antioxidants
CAPE | Inhibits NFkB activation
CAPE (104594-70-9) is an antioxidant that inhibits NFκB activation and the growth of transformed cells. CAPE inhibits lipid peroxidation and displa...$30.00 – $54.00 Select options -
Cellular Stress
Cardamonin | NFkB inhibitor
Cardamonin (19309-14-9) inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear t...$50.00 – $200.00 Select options -
Antioxidants
Celastrol | Proteasome inhibitor
Celastrol (34157-83-0) displays potent antioxidant and anti-inflammatory activity. Inhibits NFkB (IC50=270 nM). It induces heat shock response and...$50.00 – $200.00 Select options -
Cancer
DMAPT | NFkB inhibitor
DMAPT (870677-05-7) is a water soluble analog of the natural plant product parthenolide (Cat.# 10-2096) which suppresses in vivo tumor growth of tw...$45.00 – $175.00 Select options -
Cellular Stress
Helenalin | NFkB inhibitor
Helenalin (6754-13-8) is a novel sesquiterpene lactone which inhibits NFκB1 and displays potent anti-inflammatory activity2. It suppresses essentia...$238.00 Select options -
Cancer
Rocaglamide | TNFalpha inhibitor
Rocaglamide (84573-16-0) is a potent inhibitor of NFκB in T-lymphocytes with almost complete inhibition at 200nM.1 It was able to completely inhib...$60.00 – $240.00 Select options -
New Products
Roxatidine | Histamine H2 antagonist, antiulcer, anti-inflammatory
Roxatidine (78273-80-0) is a novel histamine H2 receptor antagonist.1 Suppresses inflammatory responses via inhibition of NFκB and p38 MAPK activat...$90.00 – $360.00 Select options -
Adipogenesis
SirtAct | Sirt1 activator
SirtAct (839699-72-8) is a Sirt1 activator (233% at 10 μM)1 Suppresses TNFα release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells1. S...$80.00 – $320.00 Select options -
Approved Drugs
Sivelestat | Leukocyte elastase inhibitor
Sivelestat (127373-66-4) is a potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other protease...$50.00 – $200.00 Select options
