Potassium
Showing 1–12 of 19 results
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Cardiovascular
1-EBIO | K+ channel activator; Promotes cardiomyocyte differentiation
1-EBIO (10045-45-1) is a direct activator of small-conductance Ca2+-activated K+ channels (SK) which dose-dependently relaxes rat mesenteric vessel...$40.00 – $148.00 Select options -
Ions and other channels
Cereulide | Mitochondrial toxin
Cereulide (CAS 157232-64-9) is an emetic toxin produced by Bacillus cereus. Acts as an ionophore with high selectivity for K+. Stimulates swelling ...$264.00 Select options -
Ion channels
Cromakalim | ATP-sensitive potassium channel opener
Cromakalim (94470-67-4) is a potent and selective ATP-sensitive potassium channel (KATP or Kir6) opener.1 Dose dependently prevents or suppresses h...$48.00 – $190.00 Select options -
Approved Drugs
Diazoxide | K-ATP channel activator
Activates ATP-dependent K+ channels1 via inducing translocation of PKC-epsilon from the cytosol to the mitochondria2. Hyperglycemic agent. Induces ...$40.00 – $120.00 Select options -
Approved Drugs
Dofetilide | hERG channel blocker
Dofetilide (115256-11-6) is a clinically useful class III antiarrhythmic that inhibits the rapid component of the delayed rectifier outward potassi...$65.00 – $260.00 Select options -
Arrhythmia
E-4031 | hERG channel blocker
E-4031 (113558-89-7) is a selective hERG potassium channel blocker. Inhibits the rapid delayed-rectifier K+ current (IKr). Class III antiarrhythmic...$98.00 – $392.00 Select options -
GABA
Flupirtine maleate | K+ channel activator
flupirtine maleate (75507-68-5) activates KV7 potassium channels1, indirectly antagonizes NMDA receptors and modulates GABAA receptors2. Displays n...$55.00 – $100.00 Select options -
Addiction
GBR-12909 2HCl | Dopamine reuptake inhibitor
GBR-12909 2HCl (67469-78-7) is a potent and selective inhibitor of dopamine reuptake (Ki = 1 nM) with greater than 100 fold selectivity over seroto...$60.00 – $240.00 Select options -
Approved Drugs
Glyburide | K-ATP channel blocker
Glyburide (10238-21-8) is a second generation oral hypoglycemic agent. Acts via ATP-dependent K+ channel (Kir6, KATP) block.1 Inhibits Kir6 current...$30.00 – $50.00 Select options -
Ion channels
ICA-110381 | Kv7.2/7.3 activator
ICA-110381 (325457-99-6) is a KCNQ2/Q3 (Kv7.2/7.3) activator, EC50=0.38 μM (KCNQ1 IC50=15 μM)1. KCNQ3/Q5 heterodimers are not affected2. Potently d...$55.00 – $220.00 Select options -
Ion channels
ML297 | GIRK inhibitor
ML297 (1443246-62-5) is a selective GIRK 1/2 (Kir3.1/3.2) channel activator, IC50 = 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respective...$70.00 – $280.00 Select options -
ATPase
Nigericin Na | Induces rapid intracellular acidification
Nigericin Na (28643-80-3) is a polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Induces apopto...$50.00 – $150.00 Select options
