TRP
Showing 1–12 of 22 results
-
Ion channels
2-APB | TRP activator
2-APB (524-95-8) is an IP3 receptor antagonist (IC50=42 μM).1 Inhibits store-operated Ca2+ channels at high concentrations (50 μM) but stimulates a...$25.00 – $50.00 Select options -
Ion channels
A-967079 | TRPA1 blocker
A-967079 (1170613-55-4) is a TRPA1 antagonist. Active in rat models.1 Cell permeable References/Citations 1) McGaraughty et al. (2010), TRPA1 m...$78.00 – $312.00 Select options -
Ions and other channels
AC1903 | TRPC5 blocker
AC1903 (831234-13-0) is a potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of...$70.00 – $280.00 Select options -
Ion channels
AP-18 | TRPA1 blocker
AP-18 (55224-94-7) is a selective TRPA1 (transient receptor potential A1) channel blocker (IC50 = 3.1 and 4.5 μM at human and mouse TRPA1 respectiv...$70.00 – $280.00 Select options -
Ion channels
BCTC | TRPV1 blocker
BCTC (393514-24-4) is a vanilloid receptor I (TRPV1) antagonist, IC50 = 35 nM for capsaicin-induced and 6 nM for acid-induced TRPV1 activation. Dis...$70.00 – $280.00 Select options -
Inflammation
Capsaicin (natural) | TRPV1 agonist
Capsaicin (404-86-4) is a vanilloid agonist known to activate the transient receptor potential channel vanilloid subfamily member 1 (TRPV1)1,2 and ...$80.00 – $324.00 Select options -
Inflammation
Evodiamine | TRPV1 agonist, anti-inflammatory, antiangiogenic
Evodiamine (518-17-2) is a quinolone alkaloid isolated from Evodia rutaecarpa.1 Evodia Rutaecarpa is a very popular herb used in traditional chines...$30.00 – $90.00 Select options -
Ion channels
GSK-1016790A | TRPV4 channel blocker
GSK-1016790A (942206-85-1) is a novel and potent TRPV4 channel agonist. GSK-1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK ce...$68.00 – $218.00 Select options -
Ions and other channels
GSK1702934A | TRPC 3/6 activator
GSK1702934A is a TRPC3 activator. In whole-cell patch-clamp experiments in HEK293 cells transduced with recombinant human TRPC3 or TRPC6, GSK-1702...$110.00 – $440.00 Select options -
Ion channels
GSK417651A | TRPC3/6 blocker
GSK417651A is a TRPC inhibitor. In whole-cell patch-clamp experiments in HEK293 cells transfected with recombinant human TRPC3 or TRPC6, GSK417651A...$100.00 – $400.00 Select options -
Ion channels
HC-030031 | TRPA1 blocker
HC-030031 (349085-38-7) inhibits TRPA1 channel. References/Citations 1) McNamara et al. (2007), TRPA1 mediates formalin-induced pain; Proc. Nat...$50.00 – $145.00 Select options -
Ion channels
HC-067047 | TRPV4 blocker
HC-067047 (883031-03-6) is a potent reversible and selective TRPV4 antagonist. Active at mouse, human and rat TRPV4, IC50 = 17, 48 and 133 nM respe...$58.00 – $230.00 Select options
