7-Cl-O-Nec1 | RIP1 inhibitor
7-Cl-O-Nec1 (852391-15-2) is a necrostatin-1 (Cat.# 10-1162) analogue with superior potency (IC50 = 206nM vs 494nM), selectivity and metabolic stab...
$50.00 – $185.00
A-769662 | AMPK activator
A-769662 (844499-71-4) is a potent and reversible AMP-activated protein kinase (AMPK) allosteric activator. Activates AMPK by binding to the β and...
$72.00 – $250.00
ANA-12 | TrkB antagonist
ANA-12 (219755-25-3) is a TrkB receptor antagonist. Binds to two distinct receptor sites preventing activation by BDNF non-competitively, IC50 = 45...
$75.00 – $220.00
AZ3146 | Mps1 kinase inhibitor
AZ3146 (1124329-14-1) is a potent (IC50 = 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1 Mps1 has an essential role in the ...
$60.00 – $195.00
Binimetinib | MEK1/2 inhibitor
Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of...
$39.00 – $115.00