SC-514 | IKK-2 inhibitor

SC-514 (354812-17-2) is a reversible, competitive inhibitor of IKK2 (IC50 = 11.2 μM). Has not been demonstrated to inhibit other IKK isoforms, or other kinases. SC-514 displays dose-dependent inhibition of the transcription of NF-κB dependent genes in cell culture1.

References/Citations
1) Kishore et al. (2003), A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts; J. Biol. Chem., 278 32861

Weight 0.01 mg
Dimensions 0.01 × 0.01 × 0.01 cm
Size:

10 mg, 50 mg

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CAS:
354812-17-2
Catalog Number:
10-1054
Activity:
IKK-2 inhibitor
Chemical Name:
5-(Thien-3-yl)-3-aminothiophene-2-carboxamide
Molecular Weight:
224.3
Molecular Formula:
C9H8N2OS2
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

SC-514 | IKK-2 inhibitor

$65.00$260.00

CAS:
354812-17-2
Catalog Number:
10-1054
Activity:
IKK-2 inhibitor
Chemical Name:
5-(Thien-3-yl)-3-aminothiophene-2-carboxamide
Molecular Weight:
224.3
Molecular Formula:
C9H8N2OS2
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
  • 10 mg
  • 50 mg
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