my account
  Loading... Please wait...


The phosphorylation state of a biologically relevant molecule affects its activity, reactivity, and ability to interact with other molecules. The enzymes responsible for adding phosphate groups, kinases, act on many types of molecules including proteins, lipids, carbohydrates, and nucleotides. These kinases mediate multiple signal transduction pathways and are responsible for modulating many essential cellular functions including metabolism, proliferation, differentiation, and survival. Dysfunction of kinases is involved in many pathological states including cancer, neurodegeneration, inflammation, metabolic and developmental disorders, and autoimmune diseases.

View All Kinase Reagents

View Kinase Inhibitor Library


  • R428

    AXL inhibitor that suppresses myeloid cell activation

  • Pexidartinib

    Dual inhibitor of CSF1R and c-KIT; Inhibits suppression of antitumor immunity

  • Galunisertib

    TGF-β kinase inhibitor that reverses TGF-β and Treg mediated T cell suppression

View All Immuno-Regulatory Kinase Reagents


  • PFK15

    PFK15 is a phosphofructo-2-kinase (PFKFB3) inhibitor. Antagonizes glucose and F26BP uptake

  • GSK2334470

    GSK2334470 is a potent and selective PDK1 inhibitor.

  • NU7441

    DNA protein kinase inhibitor

View All Metabolic Kinase Reagents

Cell Cycle / Cell Division

  • Ribociclib

    Clinically useful inhibitor of CDK4/6

  • RO-3306

    RO-3306 is a selective inhibitor of CDK1

  • Alisertib

    Alisertib is a potent and selective inhibitor of Aurora A kinase

View All Cell Cycle / Cell Division Kinase Reagents

Growth Factor

  • Afatinib

    Potent and highly selective inhibitor of EGFR and HER2

  • NVP-BGJ398

    NVP-BGJ398 is a potent and selective-pan FGFR inhibitor

View All Growth Factor Kinase Reagents

DNA Damage Response

  • KU-55933

    KU-55933 is a potent and selective ATM kinase inhibitor

  • NU7441

    DNA protein kinase inhibitor

  • AZ20

    Potent and selective ATR kinase inhibitor

View All DNA Damage Response Kinase Reagents

Protein Kinase C

  • Enzastaurin

    Enzastaurin is a potent and selective PKCβ inhibitor

  • PMA

    PKC activator

  • NPC-15437

    Protein kinase C inhibitor which interacts with the C1 domain of PKC

View All Protein Kinase C Reagents