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  • AZD6244 | ERK inhibitor
    AZD6244 (606143-53-6) is a potent, selective, and non-ATP competitive inhibitor of MEK1/2 (IC50 MEK1 = 14 nM) and ERK 1/2 phosphorylation (IC50 = 10 nM).1,2 AZD6244 is in clinical trials for treating various cancers...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of PD 325901 MEK inhibitor | CAS 391210-10-9
    PD 325901 (391210-10-9) is a selective Non-ATP-competitive MEK inhibitor (IC50 = 0.33nM)1. Inhibits growth and/or proliferation in a variety of cancer cells.2 PD 325901 enhances self-renewal of embryonic stem cells...

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