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  • AZD8055 | mTOR kinase inhibitor
    AZD8055 (1009298-09-2) is a potent and highly selective inhibitor of mammalian target of rapamycin kinase (mTOR) kinase (IC50 = 0.8 nM).1,2  mTOR acts as a nutrient/energy/redox sensor and a controller of protein...

  • INK-128 | TORC1/2 inhibitor
    INK-128 (1224844-38-5) is a potent and selective, ATP-competitive inhibitor of mTOR kinase, Ki = 1.4 nM.1 Inhibits growth and proliferation of various breast cancer cell lines and human endothelial cells.2...

  • MHY1485 | 326914-06-1 | Structure | Supplier
    MHY1485 (326914-06-1) is an mTOR activator. Suppresses autophagy by inhibiting the fusion of autophagosomes with lysosomes leading to the accumulation of enlarged autophagosomes.1 Increases ovarian follicle development.2...

  • Focus Biomolecules supplier, chemical structure of NVP-BEZ235 | PI 3-K and mTOR inhibitor | CAS 915019-65-7
    NVP-BEZ235 (915019-65-7) is a dual PI3K and mTOR kinase inhibitor.1 It inhibits VEGF-induced proliferation and angiogenesis.2 Reverses lapatinib resistance.3 It induces G1 arrest and reduces cyclin D1...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Rapamycin | mTOR inhibitor | CAS 53123-88-9
    Rapamycin (53123-88-9) is a clinically useful immunosuppressant. Inhibits the response to interleukin-2 blocking activation of T- and B-cells.1 Rapamycin forms a complex with cytosolic FK-binding protein 12 (FKB12) that...

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