Membrane transporters
ABC Adenine nucleotide Amino acid F-ATPase Glucose Monoamine P-ATPase V-ATPase Other Membrane Transporters
Showing 1–12 of 20 results
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ATPase
Bafilomycin A1 | Vacuolar H+ ATPase inhibitor
Bafilomycin A1 (88899-55-2) is a macrolide antibiotic derived from Streptomyces griseus that is a potent and selective inhibitor of vacuolar H+-ATP...$40.00 – $160.00 Select options -
Approved Drugs
Dipyridamole | Pan-specific PDE inhibitor
Dipyridamole (58-32-2) is a phosphodiesterase inhibitor (IC50=0.37, 0.38, 0.45, 0.9 and 4.5 μM for PDE11, 6, 10, 5 and 8 respectively.1,2 Potent eq...$22.00 Select options -
Approved Drugs
Ezetimibe | Cholesterol absorption inhibitor
Ezetimibe (163222-33-1) inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) pr...$45.00 – $140.00 Select options -
Cancer
Fasentin | Glucose uptake inhibitor
Fasentin (392721-37-8) is a novel inhibitor of glucose uptake which acts via inhibition of the glucose transporter GluT1 and GluT4 (IC50=68 μM).1 I...$55.00 – $195.00 Select options -
Cancer
Geldanamycin-FITC | HSP90 fluorescent probe
Geldanamycin-FITC is a novel geldanamycin fluorescent probe1 that may be used in a fluorescence polarization assay for HSP-90 inhibitors.2,3 May al...$200.00 Select options -
Calcium Signaling
KB-R7943 mesylate | TRPC channel blocker
KB-R7943 (182004-65-5) is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50's = 1.2-2.4 μM in cardiomyocytes, s...$65.00 – $260.00 Select options -
Cancer
Ko-143 | BCRP inhibitor
A potent and selective inhibitor of the breast cancer resistance protein multidrug transporter (BCRP/ABCG2)1. Reverses resistance of MTX and topote...$100.00 – $450.00 Select options -
Cancer
Lipofermata | Fatty acid transport protein 2 (FATP2) inhibitor
Lipofermata (297180-15-5) is an inhibitor of fatty acid transport protein 2 (FATP2; IC50 = 4.84 µM).1 It does not inhibit glucose transport or the ...$65.00 – $225.00 Select options -
Atherosclerosis
Manzamine A | Inhibitor of vacuolar ATPases
Manzamine A (104196-68-1) inhibits vacuolar ATPases and inhibits autophagy in pancreatic cancer cells1. Suppresses atherosclerosis in vivo2. Manzam...$185.00 – $740.00 Select options -
Cancer
MRL-24 | PPAR gamma partial agonist
MRL-24 displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogen...$65.00 – $260.00 Select options -
ATPase
Nigericin Na | Induces rapid intracellular acidification
Nigericin Na (28643-80-3) is a polyether ionophore which disrupts membrane potential and stimulates ATPase activity in mitochondria. Induces apopto...$50.00 – $150.00 Select options -
ATPase
Oligomycin Complex | Mitochondrial ATPase inhibitor
Oligomycin (1404-19-9) inhibits mitochondrial F1F0 ATP synthase.1 A useful tool for decreasing cellular ATP levels.2 Induces autophagy.3 Stimulates...$57.00 – $228.00 Select options
