Respiratory Chain
Showing all 9 results
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Cancer
Artesunate | Kills cancer stem cells / Depolarizes mitochondria
Artesunate (88495-63-0) is a semisynthetic derivative of the natural product artemisinin which is clinically useful for treatment of malaria and ot...Read more -
Cancer
BAY 87-2243 | HIF-1 / Mitochondrial complex I inhibitor
BAY 87-2243 (1227158-85-1) potently inhibits HIF-1 reporter gene activity (IC50 = 0.7 nM) and CA9 protein expression (IC50 = 2.0 nM).1 It inhibited...$60.00 – $225.00 Select options -
Cellular Metabolism
HQNO | NADH oxidase inhibitor
HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial ...$85.00 – $340.00 Select options -
Antifungals
Ilicicolin H | Cytochrome bc1 reductase inhibitor
Ilicicolin H (12689-26-8) is a potent inhibitor of the mitochondrial cytochrome bc1 reductase.1 Displays potent and broad spectrum antifungal activ...$120.00 – $750.00 Select options -
Calcium Signaling
KB-R7943 mesylate | TRPC channel blocker
KB-R7943 (182004-65-5) is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50's = 1.2-2.4 μM in cardiomyocytes, s...$65.00 – $260.00 Select options -
AMPK
Metformin HCl | Anti-diabetic agent
Metformin HCl (1115-70-4) is a clinically useful antidiabetic agent. Lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepati...$30.00 – $120.00 Select options -
Bioactive Lipids
N-Oleoylphenylalanine | Endogenous Uncoupler of Mitochondrial Respiration
N-Oleoylphenylalanine is an endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylala...$50.00 – $200.00 Select options -
Alzheimers
QNZ | NFkB inhibitor / Store operated calcium entry
QNZ (545380-34-5) was originally described as a potent inhibitor of NF-κB activation (IC50 = 11 nM) and TNF-α production (IC50 = 7 nM).1,2 It indir...$60.00 – $195.00 Select options -
Cell Cycle
TTFA | Mitochondrial Complex II inhibitor
TTFA (326-91-0) blocks the respiratory chain complex II causing inhibition of mitochondrial respiration. Respiratory chain complex II inhibition i...$25.00 – $50.00 Select options
