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Product Details

ML-324 | JMJD2 inhibitor

ML-324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons1.

References/Citations
1) Liang et al. (2013), Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med., 5 167ra5

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ML-324 | 1222800-79-4 | Structure | Supplier

Catalog#  10-1455

$80.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
1222800-79-4
Catalog Number:
10-1455
Activity:
JMJD2 inhibitor
Chemical Name:
N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide hydrochloride
Molecular Weight:
385.9
Molecular Formula:
C21H23N3O2 HCl
Solubility:
Soluble in DMSO (up to 20 mg/ml) or in Water (up to 25 mg/ml).
Physical Properties:
Olive solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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