Alzheimers
Showing 1–12 of 31 results
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Alzheimers
27-Hydroxycholesterol | Cholesterol oxidation metabolite
27-Hydroxycholesterol (20380-11-4) is a metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxyc...$40.00 – $175.00 Select options -
Alzheimers
ABT-418 HCl | Nicotinic acetylcholine receptor agonist; cognition enhancer
ABT-418 (CAS 147388-83-8) is an agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC5...$90.00 – $360.00 Select options -
Alzheimers
Anle138b | Protein aggregation inhibitor
Anle138b is an aggregation inhibitor that modulates the formation of pathological oligomers of both prion and α-synuclein.1 In mouse models of prio...$55.00 – $195.00 Select options -
Alzheimers
AR-A 014418 | GSK-3 inhibitor
AR-A 014418 (487021-52-3) is a selective glycogen synthase kinase 3 (GSK-3) inhibitor, IC50 = 104 nM. Inhibits β-amyloid-mediated neurodegeneration...$65.00 – $260.00 Select options -
Alzheimers
Bexarotene | Retinoid RXR agonist
Bexarotene (153559-49-0) is a highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRα, β, γ respectively).1 Clin...$40.00 – $180.00 Select options -
Alzheimers
BML-259 | CDK5/p25 inhibitor
BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1 References/Citations 1) Helal et al. (2004) Dis...$60.00 – $240.00 Select options -
Alzheimers
Compound 115-7c | HSP70 modulator
Compound 115-7c (908074-72-6) acts as an artificial co-chaperone for HSP70.1 The activity of compound 115-7c mirrors those of HSP40 stimulating the...$90.00 – $360.00 Select options -
Alzheimers
DAPT | gamma-secretase inhibitor
DAPT (208255-80-5)is an inhibitor of γ-secretase (IC50 in human primary neurons = 115 nM for total Aβ or 200 nM for Aβ42 specifically)1. Oral admin...$60.00 – $195.00 Select options -
Alzheimers
Deferiprone | Iron Chelator
Deferiprone (30652-11-0) is a clinically useful iron chelator.1 It attenuated blood-brain-barrier breakdown and brain mitochondrial dysfunction in ...$20.00 Select options -
Alzheimers
FPS-ZM1 | RAGE receptor antagonist
FPS-ZM1 (945714-67-0) is a high-affinity RAGE (Receptor for Advanced Glycation End products) receptor antagonist (IC50 = 0.6 μM). It lowers levels ...$55.00 – $225.00 Select options -
Alzheimers
Galanthamine HBr | Acetylcholinesterase inhibitor
Galanthamine HBr (1953-04-4) is a long-acting, centrally active acetylcholinesterase inhibitor, IC50 = 410 nM1. Allosteric potentiator at neuronal ...$25.00 – $100.00 Select options -
Alzheimers
Ibotenic acid | NMDA and mGluR agonist
Ibotenic acid (60573-88-8) is a conformationally restricted analog of glutamate which occurs naturally in Amanita mascaria and related mushrooms. ...$50.00 – $200.00 Select options
