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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of AK-7 | SIRT2 inhibitor | CAS 420831-40-9
    $50.00
    AK-7 (420831-40-9) is a selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt3.1 It down regulates cholesterol biosynthesis genes in primary striatal neurons.1 AK-7 displays...

  • Focus Biomolecules reagent supplier, chemical structure of Gabapentin lactam | Neuroprotective agent | CAS 64744-50-9
    $58.00
    Gabapentin lactam (CAS 64744-50-9) reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington’s disease.1 Displays neurotrophic effects, enhancing the formation of dendritic...

  • Focus Biomolecules supplier, chemical structure of Minocycline HCl | Neuroprotective | Antiapoptotic | CAS 13614-98-7
    $38.00
    Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. Reduces MMP-9 activity2. Attenuates disease severity in mouse models of...

  • Pridopidine | Sigma-1 ligand Neuroprotectant/Neurorestorative
    $80.00
    Pridopidine is being studied as a potential treatment for Huntington’s disease, Parkinson’s disease, and schizophrenia based on its locomotor stabilizing and antipsychotic-like effects.1,2 It was, unusually, able...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of SMER28 | Autophagy inducer | CAS 307538-42-7
    $38.00
    SMER28 (CAS 307538-42-7) Induces autophagy via an mTOR-independent pathway. Enhances clearance of b-amyloid protein in cell lines and primary neuronal culture models.1-3  May be a useful lead compound for the...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Tetrabenazine | VMAT2 inhibitor | CAS 58-46-8
    $30.00
    Tetrabenazine (58-46-8) is a potent inhibitor of the vesicular monoamine transporter (VMAT), IC50=3.2 nM1,2 with selectivity for VMAT2 over VMAT13. Promotes late stage differentiation of Pdx1-positive pancreatic progenitor...

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