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Multiple sclerosis

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  • Focus Biomolecules supplier, chemical structure of Benztropine mesylate | Induces remyelination of neurons | CAS 132-17-2
    Benztropine mesylate (132-17-2) is a centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat).1 Also inhibits the dopamine transporter (Ki=160 nM).2 Benztropine mesylate enhances remyelination and...

  • BI-D1870 | p90 ribosomal S6 kinase inhibitor
    BI-D1870 (501437-28-1) is an inhibitor of p90 ribosomal S6 kinase (RSK; IC50’s = RSK1, 31 nM; RSK2, 24 nM; RSK3, 18 nM; RSK4, 15 nM) with selectivity over other AGC kinases.1 It protected mice from experimental...

  • Focus Biomolecules supplier, chemical structure of FTY720 HCl | Sphingosine-1-phosphate receptor agonist | CAS 162359-56-0
    FTY720 HCl (162359-56-0) is an analog of sphingosine (Cat.# 10-2287) which, when taken up into cells, is phosphorylated and acts as an agonist at sphingosine-1-phosphate receptors (S1P1/3).1 Potently inhibits regulatory...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of MDL29,951 | GPR17 activator | CAS 130798-51-5
    MDL29,951 (130798-51-5) is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17...

  • Focus Biomolecules supplier, chemical structure of Minocycline HCl | Neuroprotective | Antiapoptotic | CAS 13614-98-7
    Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. Reduces MMP-9 activity2. Attenuates disease severity in mouse models of...

  • Nimodipine | L-type calcium channel blocker
    Nimodipine (66085-59-4) is an L-type calcium channel blocker.1 Prevents age-induced learning deficits in a rat model.2 Facilitates recovery of function after brain damage3 and displays neuroprotective effects4. Promotes...

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