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  • AM251 | Cannabinoid CB1 antagonist
    AM251 (183232-66-8) is a potent cannabinoid CB1 receptor antagonist with selectivity over CB2 receptors (306-fold).1-3 Displays anorectic effects and antidepressant-like effects in mice.4 Behaves as an agonist at GPR55,...

  • Anandamide | Endogenous cannabinoid
    Anandamide (94421-68-8) is an endogenous cannabinoid receptor agonist.1-3 Ki=89 nM for CB1 and 371 nM for CB2 receptors. References/Citations1) Devane et al. (1992), Isolation and structure of a brain constituent that binds...

  • JZL-184 | 1101854-58-3 | Structure | Supplier
    JZL-184 (1101854-58-3) inhibits MAG lipase (IC50=8 nM) selectively over FAAH. Irreversible. Cell permeable. References/Citations1) Long et al. (2009), Selective blockade of 2-arachidonoylglycerol hydrolysis produces...

  • LY-2183240 | Anandamide uptake inhibitor
    LY-2183240 (874902-19-9) is highly potent inhibitor of cellular anandamide uptake (IC50 = 0.27nM1, 15nM2). LY-2183240 has also been found2,3,4 to be an inhibitor of fatty acid amide hydrolase (FAAH) - IC50 = 14nM4,...

  • Palmitoylethanolamine | 544-31-0 | Structure | Supplier
    Palmitoylethanolamide (544-31-0) is an endogenous cannabinoid. Weak ligand for CB1 (Ki= 23.8 μM) and CB2 (Ki = 13.9 μM) receptors. Inhibits fatty acid amide hydrolase (FAAH) ((IC50 = 5.1 μM). Modulates mast cell...

  • Rimonabant | 168273-06-1 | Structure | Supplier
    Rimonabant (168273-06-1) is a selective CB1 receptor inverse agonist (Ki = 1.8 nM).1,2 It is an anorectic antiobesity drug originally approved for use in Europe but eventually withdrawn from the market because of potential...

  • SR-144528 | 192703-06-3 | Structure | Supplier
    SR-144528 (192703-06-3) is a potent and selective antagonist of the cannabinoid CB2 receptor1,2. References/Citations1) Rinaldi-Carmona et al. (1998), SR-144528, the first potent and selective antagonist of the CB2...

  • WIN-55212-2 mesylate | 131543-23-2 | Structure | Supplier
    WIN-55212-2 mesylate (131543-23-2) is a high affinity cannabinoid receptor agonist (Ki = 62.3 nM for recombinant human CB1 and 3.3 nM for recombinant human CB2)1 with analgesic2 and anti-inflammatory activities. WIN-55212-2...

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