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Showing 1–12 of 161 results
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(+)-Cedrol | Anticancer natural product
Cedrol is a sesquiterpene alcohol found in conifers mainly of the genera Cupressus, Juniperus, and Cedrus. It has been found to possess significant...$30.00 – $80.00 Select options -
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1G244 | DPP8/9 inhibitor
1G244 (847928-32-9) is a potent and selective inhibitor of the prolyl dipeptidases DPP8 (IC50 = 14 nM) and DPP9 (IC50 = 53 nM).1,2 It does not inh...$70.00 – $270.00 Select options -
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2-AAPA | Glutathione/thioredoxin reductase inhibitor
2-AAPA (1133387-90-2) inhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial functio...$60.00 – $240.00 Select options -
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5-Thio-D-glucose | Glucose transport inhibitor
5-Thio-D-glucose (20408-97-3) is a potent competitive inhibitor of the cellular transport of glucose and glucose-mediated insulin release.1 May be ...$80.00 – $320.00 Select options -
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A-438079 HCl | P2X7 antagonist
A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pa...$60.00 – $225.00 Select options -
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ABX-1431 | MAGL inhibitor
ABX-1431 (1446817-84-0) is a potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold o...$60.00 – $235.00 Select options -
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Acalabrutinib | Highly selective BTK inhibitor
Acalabrutinib (1420477-60-6) is a highly selective, potent (IC50 = 3 nM), and irreversible inhibitor of Bruton’s tyrosine kinase (BTK).1 Improved t...$45.00 – $145.00 Select options -
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AE 51310 | OPN4/melanopsin antagonist
AE 51310 (433966-92-8) is a potent antagonist of the GPCR OPN4/melanopsin (Ki = 0.096 nM human OPN4).1 OPN4 regulates circadian rhythms, pupil func...$50.00 – $195.00 Select options -
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Apilimod | IL-12 and 23/PIKfyve inhibitor
Apilimod (541550-19-0) is a potent (IC50 = 10 nM IFN-g/LPS-stimulated human PMBC’s; IC50 = 1 nM in IFN-g/SAC-stimulated human PMBC’s) IL-12/IL-23 i...$45.00 – $160.00 Select options -
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AR7 | Activates chaperone mediated autophagy
AR7 (80306-38-3) is an atypical retinoid which acts as an RARα antagonist and activates chaperone-mediated autophagy (CMA) via an RAR-dependent pat...$70.00 – $280.00 Select options -
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AS-1949490 | SHIP2 inhibitor
AS-1949490 (1203680-76-5) is a potent and selective inhibitor of the intracellular phosphatase SHIP2 (SH2 domain-containing inositol 5'-phosphatas...$62.00 – $248.00 Select options -
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Autogramin-2 | Autophagy blocker / GRAMD1A inhibitor
Autogramin-2 (2375541-45-8) is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting...$70.00 – $275.00 Select options
