Apixaban | Factor Xa inhibitor
CAS:
503612-47-3
Catalog Number:
10-5660
Activity:
Factor Xa inhibitor
Chemical Names:
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Molecular Weight:
459.51
Molecular Formula:
C25H25N5O4
Solubility:
Soluble in DMSO (40 mg/ml)
Physical Properties:
White solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $50.00 | ||
| 25mg | $185.00 |
Apixaban (503612-47-3) is a potent and selective inhibitor of both free and prothrombin-bound factor Xa, Ki = 0.8 nM.1 Clinically useful antithrombotic agent.2 Apixaban lowered risk of recurrent venous thromboembolism and major bleeding in high-risk patients.3
References/Citations:
- Turpie et al. (2007), Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases; Arterioscler. Vasc. Biol., 27 1238
- Lai et al. (2022), Effects of oral anticoagulant therapy in patients with pulmonary diseases; Front. Cardiovasc. Med., 9 987652
- Cohen et al. (2022), Effectiveness and safety of apixaban vs warfarin among venous thromboembolism patients at high-risk of bleeding; PLoS One, 17 e0274969
CAS:
503612-47-3
Catalog Number:
10-5660
Activity:
Factor Xa inhibitor
Chemical Names:
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Molecular Weight:
459.51
Molecular Formula:
C25H25N5O4
Solubility:
Soluble in DMSO (40 mg/ml)
Physical Properties:
White solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Safety Data Sheet:
N/A
Product Data Sheet:
N/A
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Apixaban (503612-47-3) is a potent and selective inhibitor of both free and prothrombin-bound factor Xa, Ki = 0.8 nM.1 Clinically useful antithrombotic agent.2 Apixaban lowered risk of recurrent venous thromboembolism and major bleeding in high-risk patients.3
References/Citations:
- Turpie et al. (2007), Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases; Arterioscler. Vasc. Biol., 27 1238
- Lai et al. (2022), Effects of oral anticoagulant therapy in patients with pulmonary diseases; Front. Cardiovasc. Med., 9 987652
- Cohen et al. (2022), Effectiveness and safety of apixaban vs warfarin among venous thromboembolism patients at high-risk of bleeding; PLoS One, 17 e0274969
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
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