Bepridil | Calcium channel blocker\Active against SARS-CoV2

Bepridil is a clinically useful calcium channel blocker with antianginal activity.1 It has recently been shown to possess potent activity against SARS-CoV-2 in vitro.2 Bepridil was also able to provide protection from Ebola virus3 and other filoviruses in a mouse model4.

References:

  1. Hollingshead et al. (1992), A review of its pharmacological properties and therapeutic use in stable angina pectoris; Drugs, 44 835
  2. Vatansever et al. (2021), Bepridil is potent against SARS-CoV-2 in vitro; Proc. Natl. Acad. Sci USA, 118 e2012201118
  3. Johansen et al. (2015), A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity; Sci. Transl. Med., 7 290ra89
  4. DeWald et al. (2018), The calcium channel blocker bepridil demonstrates efficacy in the murine model of marburg virus disease; Infect. Dis., 218(suppl 5) S588
Weight 0.01 mg
Dimensions 0.01 × 0.01 × 0.01 cm
Size:

5 mg, 25 mg

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CAS:
74764-40-2
Catalog Number:
10-4958
Activity:
Calcium channel blocker/anti-SARS-CoV2
Chemical Name:

N-Benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline hydrochloride

Molecular Weight:
403.00
Molecular Formula:
C24H34N2O·HCl
Solubility:
Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Bepridil | Calcium channel blocker\Active against SARS-CoV2

$40.00$125.00

CAS:
74764-40-2
Catalog Number:
10-4958
Activity:
Calcium channel blocker/anti-SARS-CoV2
Chemical Name:

N-Benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline hydrochloride

Molecular Weight:
403.00
Molecular Formula:
C24H34N2O·HCl
Solubility:
Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
>98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
  • 5 mg
  • 25 mg
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