GRL-0667 | Noncovalent inhibitor of SARS-CoV PLpro
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $95.00 | ||
| 25 mg | $370.00 |
GRL-0667 (1234195-91-5) is a potent (IC50 = 320 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL-0667 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 9.1 µM).1
References:
- Ghosh et al. (2010), Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Novel Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation; J. Med. Chem. 53 4968
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
GRL-0667 (1234195-91-5) is a potent (IC50 = 320 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL-0667 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 9.1 µM).1
References:
- Ghosh et al. (2010), Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Novel Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation; J. Med. Chem. 53 4968
Related products
-
Resiniferatoxin | TRPV1 activator
From $115.00CAS:57444-62-9Catalog Number:10-2103Activity:TRPV1 activatorChemical Names:RTXMolecular Weight:628.71Molecular Formula:C37H40O9Solubility:Soluble in DMSO (65 mg/ml) or ethanol (30 mg/mL)Physical Properties:Off-white waxy solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
Pomalidomide | Cereblon ubiquitination inhibitor
From $50.00CAS:19171-19-8Catalog Number:10-2768Activity:Cereblon ubiquination inhibitorChemical Name:1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline; 3-amino-N-(2,6-dioxo-3-piperidyl)phthalamideMolecular Weight:273.24Molecular Formula:C13H11N3O4Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
SNS-314 mesylate | Aurora kinase inhibitor
From $70.00CAS:1146618-41-8Catalog Number:10-4779Activity:Aurora kinase inhibitorChemical Name:1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylateMolecular Weight:527.04Molecular Formula:C18H15ClN6OS2 • CH3SO3HSolubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
Website Created by Advanta Advertising LLC.