N-Acetyl-L-cysteine | Antioxidant
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 g | $25.00 | ||
| 25 g | $58.00 |
N-Acetyl-L-cysteine (616-91-1) is a thiol-containing antioxidant.1 N-Acetyl-L-cysteine acts as a scavenger of reactive oxygen species (ROS) and is commonly used to decrease oxidative stress in various models.2 Inhibits ROS-dependent apoptosis.3 Displays protective effects in various disease models including renal ischemia/reperfusion injury4, hepatic failure5 and others. Has been shown to interfere with and antagonize the activity of proteasome inhibitors.6
References/Citations:
- Merck Index 14 88
- Mlejnek et al. (2022), Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophile – An Overlooked In Vitro Mechanism of Protection; Antioxidants (Basel), 11 1485
- Curtin et al. (2002), Regulation and measurement of oxidative stress in apoptosis; J. Immunol. Methods, 265 49
- Sehirli et al. (2003), Protective effect of N-acetylcysteine on renal ischemia/reperfusion injury in the rat; J. Nephrol. 16 75
- Ritter et al. (2004), Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced hepatic failure in rats; Crit. Care Med. 32 2079
- Halasi et al. (2033), ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors; Biochem. J. 454 201
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
N-Acetyl-L-cysteine (616-91-1) is a thiol-containing antioxidant.1 N-Acetyl-L-cysteine acts as a scavenger of reactive oxygen species (ROS) and is commonly used to decrease oxidative stress in various models.2 Inhibits ROS-dependent apoptosis.3 Displays protective effects in various disease models including renal ischemia/reperfusion injury4, hepatic failure5 and others. Has been shown to interfere with and antagonize the activity of proteasome inhibitors.6
References/Citations:
- Merck Index 14 88
- Mlejnek et al. (2022), Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophile – An Overlooked In Vitro Mechanism of Protection; Antioxidants (Basel), 11 1485
- Curtin et al. (2002), Regulation and measurement of oxidative stress in apoptosis; J. Immunol. Methods, 265 49
- Sehirli et al. (2003), Protective effect of N-acetylcysteine on renal ischemia/reperfusion injury in the rat; J. Nephrol. 16 75
- Ritter et al. (2004), Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced hepatic failure in rats; Crit. Care Med. 32 2079
- Halasi et al. (2033), ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors; Biochem. J. 454 201
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
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