Saxagliptin HCl | DPP-IV inhibitor

Saxagliptin (709031-78-7) is a clinically useful DPPIV inhibitor for the treatment of diabetes.¹Human DPP-IV Ki = 0.6 nM.²

References:

Tahrani et al. (2009) Saxagliptin: a new DPP-4 inhibitor for the treatment of type 2 diabetes mellitus; Adv. Ther. 26 249
Augeri et al. (2005) Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes; J. Med. Chem. 48 5025

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CAS:

709031-78-7

Catalog Number:

10-4076

Activity:

DPP-IV inhibitor

Chemical Names:

(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride; BMS-477118

Molecular Weight:

416.45

Molecular Formula:

C₁₈H₂₅N₃O₂·HCl

Solubility:

Soluble in DMSO (20 mg/ml)

Physical Properties:

White solid

Purity:

99% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

Name: Saxagliptin HCl | DPP-IV inhibitor
SKU: 10-4076
Availability: InStock

$39.00 – $140.00

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