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AhR

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  • Focus Biomolecules supplier, chemical structure of 6-Formylindolo[3,2-b]carbazole | AhR endogenous agonist | CAS 172922-91-7
    $49.00
    6-Formylindolo(3,2-b)carbazole (172922-91-7) is a very potent (Kd = 0.07 nM) endogenous ligand for the aryl hydrocarbon receptor (AhR).1,2 References/Citations1) Rannung et al. (1987) Certain photooxidized derivatives of...

  • Focus Biomolecules reagent supplier, chemical structure of CH-223191 | Arylhydrocarbon receptor antagonist | CAS 301326-22-7
    $55.00
    CH-221391 (CAS 301326-22-7) is an arylhydrocarbon (AhR) receptor antagonist, IC50=30 nM.1 Blocks endogenous AhR agonist-induced differentiation of Th17 cells.2   Promotes expansion of human hematopoietic stem cells...

  • Focus Biomolecules cell signaling supplier, chemical structure of Cinnabarinic acid | Endogenous AhR ligand | CAS 606-59-7
    $50.00
    Cinnabarinic acid (606-59-7) is a novel endogenous tryptophan metabolite which acts as an aryl hydrocarbon receptor (AHR) agonist.1 It drives IL-22 production by stimulating the differentiation of human and mouse T cells...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of DiMNF | AhR modulator (SAhRM) | CAS 14756-24-2
    $70.00
    DiMNF (14756-24-2) is a selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). It exhibits antiinflammatory activity including suppression of cytokine-mediated acute phase genes through dissociation of...

  • Focus Biomolecules supplier, chemical structure of Kynurenine (L) | Endogenous AhR agonist | CAS 2922-83-0
    $38.00
    Kynurenine (2922-83-0) is a tryptophan catabolite.1 Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Pifithrin alpha | p53 inhibitor | CAS 63208-82-2
    $50.00
    Pifithrin α (63208-82-2) is a reversible inhibitor of p53-mediated transcription and p53-dependent apoptosis. Enhances survival after genotoxic stress and protects against chemotherapeutic side-effects in mice.1,2...

  • Focus Biomolecules reagent supplier, chemical structure SR1 | Maintains stem cells in pluripotent state | CAS 1227633-49-9
    $35.00
    SR1 (1227633-49-9) extends the pluripotency of hematopoietic stem cells (IC50 = 127 nM) by antagonizing AhR signaling resulting in continued expression of CD34. Effects are easily reversed by the removal of the SR1...

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