Nuclear Receptors - LXR - Focus Biomolecules

20(S)-Hydroxycholesterol | Smoothened activator

$45.00

20-(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchymal stem cells mediated via a non-LXR dependent pathway.2 The osteogenic...

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24(S),25-Epoxycholesterol | LXR agonist

$75.00

24(S),25-Epoxycholesterol (77058-74-3) is a cholesterol metabolite that acts as an endogenous agonist for nuclear receptor LXR.1 Controls cellular cholesterol homeostasis.2 24(S),25-Epoxycholesterol promotes neural...

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24(S)-Hydroxycholesterol | Endogenous cholesterol metabolite

$50.00

24S Hydroxycholesterol (474-73-7) is an important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain.1 It is an endogenous agonist of the nuclear receptor LXR.2 It has been shown to induce cell death in...

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27-Hydroxycholesterol | Cholesterol oxidation metabolite

$40.00

27-Hydroxycholesterol (20380-11-4) is a metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxycholesterol are elevated in patients with Alzheimers disease and mild...

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5alpha,6alpha-Epoxycholesterol | LXR ligand

$25.00

5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol. It is a major oxysterol found in processed food1 and has been implicated in atherosclerosis2,3...

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SR9243 | LXR inverse agonist

$45.00

SR9243 (1613028-81-1) is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression.1 Induces apoptosis in a variety of cancer cell types...

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LXR

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