PPAR
Showing 1–12 of 15 results
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Adipogenesis
BADGE | PPAR gamma antagonist
BADGE (1675-54-3) is a PPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes th...$30.00 – $100.00 Select options -
Adipogenesis
Ciglitazone | PPARgamma agonist
Ciglitazone (74772-77-3) is a PPARγ agonist (EC50=3 μM). Stimulates adipogenesis in human mesenchymal stem cells. Ciglitazone inhibits HUVEC differ...$80.00 – $320.00 Select options -
New Products
Elafibranor | PPARalpha/delta agonist
Elafibranor (923978-27-2) is a dual PPARα/δ agonist (EC50 PPARα = 10-20 nM; PPARδ = 100-150 nM).1 It was able to decrease plasma triglycerides leve...$65.00 – $235.00 Select options -
Cancer
FH-535 | Wnt/beta-catenin inhibitor
FH-535 (108409-83-2) suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition...$55.00 – $220.00 Select options -
Metabolic syndrome
Formononetin | PPARgamma activator; increases adipocyte thermogenesis
Formononetin (485-72-3) is a naturally occurring isoflavone isolated from Astragalus and other plants. Increases adipocyte thermogenesis by modulat...$50.00 – $150.00 Select options -
Nuclear receptors
GSK-3787 | PPARδ antagonist
GSK-3787 (188591-46-0) is a selective and irreversible antagonist of the peroxisome proliferator-activated receptor δ (PPARδ) – plC50 = 6.6. It cov...$50.00 – $200.00 Select options -
Cardiovascular
GW-501516 | PPAR delta agonist
GW-501516 (317318-70-0) is a potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces ap...$55.00 – $190.00 Select options -
Bone and Connective Tissue
GW9662 | PPAR gamma antagonist
GW9662 (22978-25-2) is a selective PPARγ antagonist (IC50 = 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively).1 Blocks the inhibition of...$45.00 – $120.00 Select options -
Bioactive Lipids
LY-171883 | Cys LT1 antagonist
LY-171883 (88107-10-2) is a selective and orally active leukotriene D4 (LTD4) antagonist (Ki = 0.63 μM).1 It is also an activator of peroxisome pro...$60.00 – $240.00 Select options -
Bioactive Lipids
MK-886 | FLAP inhibitor
MK-886 (118414-82-7) is an inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibiti...$70.00 – $280.00 Select options -
Bioactive Lipids
Oleamide | Endogenous sleep-inducing lipid
OOleamide (301-02-0) was originally identified in the cerebrospinal fluid of sleep-deprived cats acting as an inducer of physiological sleep in ani...$48.00 – $158.00 Select options -
Approved Drugs
Pioglitazone HCl | PPAR gamma agonist
Pioglitazone (112529-15-4) is a clinically useful antidiabetic drug.1 It is a selective agonist of the human peroxisome proliferator-activated rece...$30.00 – $100.00 Select options
