my account
  Loading... Please wait...

Other metabolic diseases

Sort by
  • Conduritol B epoxide | 6090-95-5 | Structure | Supplier
    Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4. References/Citations 1) Datta and Radin...

  • Isofagomine tartrate | Glucocerebrosidase activator and chaperone
    Isofagomine tartrate (957230-65-8) is a competitive inhibitor of human lysosomal β-glucosidase, IC50 = 0.06 μM.1 Increases the activity of N370S mutant acid β-glucosidase (GlcCerase) in Gaucher fibroblasts.2...

  • ML-SA1 | 332382-54-4 | Structure  | supplier
    ML-SA1 (332382-54-4) is a TRPML 1,2 and 3 channel activator.1 Does not activate TRPM2, TRPV2, TRPV3, TRPC6 or TRPA1 channels.2 ML-SA1 robustly activates whole cell TRPML1-4A and whole-endolysosome TRPML1 and is...

  • Phenylbutyrate Na | 1716-12-7 | Structure | Supplier
    Phenylbutyrate Na (1716-12-7) is a histone deacetylase (HDAC) inhibitor. Inhibits proliferation, migration and invasion of a number of cancer cell lines. Phenylbutyrate Na induces differentiation, and apoptosis. Active in...

  • U-18666A | 3039-71-2 | Structure | Supplier
    U-18666A (3039-71-2) is an oxidosqualene reductase inhibitor.1 Inhibits the egress of cholesterol from late endosomes and lysosomes.2 U-18666A is also used to study Niemann-Pick disease and for assessing the importance of...

Share Focus

Connect with Focus