We will continue to add new products to our already extensive portfolio – check back often for the latest breakthroughs. If you can’t find what you need, contact us for information on custom synthesis.

New Products
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Guggulsterone-(Z) (39025-23-5) is a natural steroid from Commiphora mukul extract (guggulipid) which lowers cholesterol and acts as an FXR antagoni...
$76.00$300.00

Remodelin (949912-58-7) is a potent and selective inhibitor of N-acetyltransferase 10 (NAT10) which is capable of acetylating microtubules and hist...
$65.00$280.00

TIC10 (1616632-77-9) is novel anti-cancer compound that acts via early-stage integrated stress response activation leading to selective cancer cell...
$50.00$195.00

Roxadustat (808118-40-3) is a pan-prolyl hydroxylase domain (PHD) inhibitor (IC50 for PHD2 = 591 nM)1 that stabilizes hypoxia-inducible factor (HIF...
$30.00$120.00

Omeprazole (73590-58-6) is a H+,K+-ATPase inhibitor (IC50 = 5.8 μM). Clinically useful antisecretory and antiulcer agent.1 Potent inhibitor of CYP2...
$38.00$98.00

GKT-137831 (1218942-37-0) is an NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1  Inhibits erastin-stimulated ROS production.2 Potentiates immun...
$70.00$280.00

Ritonavir (155213-67-5) is a clinically useful HIV-1/HIV-2 protease inhibitor.1 Potent inhibitor of cytochrome P450 3A4.2,3   References...
$40.00$150.00

Oseltamivir phosphate (204255-11-9) is a potent viral neuraminidase inhibitor and a clinically useful treatment for influenzas A and B.1,2 Oseltami...
$30.00$110.00

Tiagabine (145821-59-6) is a clinically useful anticonvulsant.1 It is also used to treat anxiety/panic disorder2 and neuropathic pain3. Tiagabine i...
$35.00$125.00

GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). ...
$90.00$325.00

Nelfinavir mesylate (159989-65-8) is a clinically useful anti-HIV agent acting via inhibition of HIV-1 protease (Ki=2 nM).1 It also displays effica...
$50.00$175.00

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Prochlorperazine maleate (84-02-6) inhibits dynamin and clathrin-mediated endocytosis (CME) with an IC50=5.8 µM for CME.1 Increases tumor cell anti...
$180.00$550.00

Favipiravir is an inhibitor of Influenza viruses A, B, and C (IC50’s: A = 0.03-0.20 µg/mL H1N1, 0.01-0.30 H2N2, 0.08-0.48 H3N2, 0.14-0.15 H4N2, 0.2...
$45.00$160.00

Ponatinib (943319-70-8) is a highly potent pan-Bcr-Abl and multikinase inhibitor, suppressing the activity of native Bcr-Abl (IC50=0.37 nM) as well...
$50.00$170.00

Tazemetostat (1403254-99-8) is a potent (Ki = 2.5nM wild type human PRC2-containing) and selective SAM-competitive inhibitor of the lysine methyltr...
$55.00$175.00

GRL-0496 (1087243-14-8) is a potent (IC50 = 30 nM in cell culture assays) inhibitor of severe acute respiratory syndrome-coronavirus chymotrypsin-l...
$60.00$225.00

Roxatidine (78273-80-0) is a novel histamine H2 receptor antagonist.1 Suppresses inflammatory responses via inhibition of NFκB and p38 MAPK activat...
$90.00$360.00

Brequinar sodium (96201-88-6) is an inhibitor of dihydroorotate dehydrogenase (DHODH)1,2 with IC50’s between 0.2 and 5.8 µM in various cell lines3 ...
$70.00$275.00

Dihydroresveratrol (58436-28-5) is a metabolite of resveratrol produced by gut microbiota.1-3 Glucoronide conjugates are found in human urine after...
$50.00$180.00

Scriptaid (287383-59-9) inhibits histone deacetylases (HDAC) 1 and 3 (IC50~0.6 μM) and HDAC8 (IC50~1 μM) and is less toxic compared to trichostatin...
$70.00$260.00

N4-Hydroxycytidine (3258-02-4) was originally identified as a mutagen effecting AT to GC base-pair transitions.1 It has also been found to have ant...
$70.00$250.00

Camostat mesilate (59721-29-8) is a serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancrea...
$40.00$125.00

PK150 (2165324-62-7) is a Sorafenib analog that displays significant antibacterial activity against several pathogenic strains (S.aureus NCTC8325, ...
$55.00$195.00

DY131 (95167-41-2) is a selective agonist at estrogen-related receptors ERRβ and ERRγ with minimal activity at ERRα, ERα and ERβ at concentrations ...
$42.00$180.00

Leelamine HCl (16496-99-4) is a lysosomotropic, intracellular cholesterol transport inhibitor with potential chemotherapeutic activity. Induces cho...
$50.00$200.00

Santacruzamate A (1477949-42-0) is a highly potent and selective inhibitor of HDAC2 isolated from the Panamanian marine cyanobacterium cf. Symploca...
$40.00$160.00

Fruquintinib (1194506-26-7) is a potent and highly selective inhibitor of VEGFR kinase (IC50’s: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 I...
$75.00$255.00

AZ20 (1233339-22-4) is a potent and highly selective inhibitor of Ataxia telangiectasia mutated and RAD3-related (ATR) kinase (IC50 = 5 nM in vitro...
$70.00$235.00

AZD1152-HQPA (722544-51-6) is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM; Aurora A Ki = 1,369 nM.2 It inhibits the...
$50.00$150.00

Lomeguatrib (192441-08-0) is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 I...
$50.00$195.00

Levetiracetam (102767-28-2) is a clinically useful non-classical anticonvulsant.1 It has no effect on voltage-dependent Na+ channels, GABAergic tra...
$45.00$70.00

Tigecycline (220620-09-7) is a clinically useful antibiotic.1,2 It is a glycylcycline derivative of minocycline that binds to the 30S ribosomal sub...
$50.00$195.00

Volasertib (755038-65-4) is an extremely potent and selective inhibitor (IC50’s: Plk1= 0.87 nM, Plk2 = 5 nM, Plk3 = 56 nM) of Polo-like kinase 1, a...
$80.00$275.00

SNS-314 mesylate (1146618-41-8) is a potent and selective pan-Aurora kinase inhibitor (IC50’s: Aurora A = 9 nM, Aurora B = 31 nM, Aurora C = 3 nM.1...
$70.00$250.00

Elafibranor (923978-27-2) is a dual PPARα/δ agonist (EC50 PPARα = 10-20 nM; PPARδ = 100-150 nM).1 It was able to decrease plasma triglycerides leve...
$65.00$235.00

Methoprene Acid (53093-52-7) is an analog of insect juvenile hormone which acts as an insect growth regulator. Binds directly and selectively to th...
$70.00$280.00

NU7441 (503468-95-9) is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK).1,2 It increased t...
$50.00$175.00

AZD7762 (860352-01-8, free base) is a potent and selective inhibitor of checkpoint kinases 1 and 2 (IC50 = 5 nM for both).1 It abrogates DNA damage...
$60.00$200.00

AZ3146 (1124329-14-1) is a potent (IC50 = 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1 Mps1 has an essential role in the ...
$60.00$195.00

NOTUM is a carboxylesterase which depalmitoylates Wnt proteins which results in disruption of Wnt signaling.1 NOTUMib-1 inhibits the carboxylestera...
$55.00$220.00

MitoBloCK-12 (522-51-0) attenuates mitochondrial protein import (4-10 μM). Discovered in a screen of FDA-approved drugs. Blocks translocation of a ...
$40.00$130.00

Two-pore domain potassium (K2P) channels of the TREK subfamily regulate neuronal excitability, influence pain, temperature perception and responses...
$55.00$220.00

DO264 is a potent, reversible competitive inhibitor of ABHD12 (α/β-hydrolase domain-containing 12) which shows negligible interaction with other se...
$70.00$280.00

N-eicosanoyl serotonin is a natural product found in coffee which synergizes with caffeine in protecting the brain in models of α-synucleinopathy1....
$50.00$180.00

Thalidomide analog. Inhibits cereblon (CRBN) an E3 ubiquitin ligase, IC50 ~3 μM for CRBN-DDB1 complex.1 Displays antiangiogenic and immunomodulator...
$50.00$150.00

Acalabrutinib (1420477-60-6) is a highly selective, potent (IC50 = 3 nM), and irreversible inhibitor of Bruton’s tyrosine kinase (BTK).1 Improved t...
$45.00$145.00

Norfluoxetine HCl (57226-68-3) is a metabolite of fluoxetine.3 Induces long QT syndrome via slow delayed rectifier potassium current block.1 Time d...
$60.00$200.00

Imiquimod (99011-02-6) is a Toll-like receptor 7/8 agonist with anti-viral and anti-tumor properties.1 Enhances innate immune system leading to Th1...
$30.00$75.00

Rucaparib phosphate (459868-92-9) is a potent (Ki<5 nM) PARP1 inhibitor.1 Cytotoxic to human cancer cells or xenograft tumors with mutated or ep...
$70.00$280.00

Ibrutinib (936563-96-1) is a very potent (IC50 = 0.5nM) irreversible inhibitor of Bruton tyrosine kinase (BTK) that blocks activation of the B-cell...
$40.00$125.00

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