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  • AM-404 | 198022-70-7 | Structure | Supplier
    AM-404 (198022-70-7) inhibits anandamide transport (IC50 = 1 μM) without inhibiting anandamide amidase or activating cannabinoid receptors.1,2 Vanilloid receptors are activated by AM-404.3 Active in vivo...

  • Celecoxib | COX II inhibitor
    Celecoxib (169590-42-5) is a selective inhibitor of cyclooxygenase-2 (COX-2) IC50 = 15 and 0.04 μM for COX-1 and COX-2 respectively.1 Potent and clinically useful antiinflammatory agent.2 Cancer chemopreventive...

  • Oxaprozin | 21256-18-8 | Structure | Supplier
    Oxaprozin (21256-18-8) is a clinically useful non-steroidal anti-inflammatory drug.1 In addition to typical NSAID COX inhibition, oxaprozin may also exert anti-inflammatory effects via inhibition of the Akt/IKK/NF-κB...

  • Rofecoxib | Selective COX-2 inhibitor
    Rofecoxib (162011-90-7) is a potent and selective COX-2 inhibitor with 1000-fold selectivity over COX-1, IC50=26 nm vs >50 μM1. Potent nonsteroidal anti-inflammatory agent1. Rofecoxib is a clinically useful NSAID which...

  • Sulindac Sulfide | NFkB inhibitor
    Sulindac sulfide (32004-67-4) is the active metabolite of cyclooxygenase inhibitor sulindac.1 Strongly inhibits Ras induced malignant transformation and Ras/Raf dependent transactivation.2 Sulindac sulfide induces apoptosis...

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