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PI-3K

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  • 3-Methyladenine | Autophagosome inhibitor
    $30.00
    3-Methyladenine (5142-23-4) inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K)1,2. Protects 1321N1 astrocytoma cells against pyocyanin and...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure AS-041164 | PI 3-Kgamma inhibitor | CAS 6318-41-8
    $60.00
    AS-041164 (6318-41-8) is a potent, ATP-competitive, and isoform-selective PI3-Kinase inhibitor (IC50 = 0.07, 0.24, 1.45, and 1.70 μM for the γ, α, β, and δ isoforms respectively).1 Cell permeable...

  • Focus Biomolecules supplier, chemical structure of LY 294002 | PI 3-Kinase inhibitor | CAS 154447-36-6
    $30.00
    LY 294002 (154447-36-6) is a potent and specific inhibitor of phosphatidylinositol-3-kinase (IC50 = 1.40 μM). References/Citations1) Vlahos et al. (1994) A specific inhibitor of phosphatidylinositol 3-kinase,...

  • Focus Biomolecules supplier, chemical structure of NVP-BEZ235 | PI 3-K and mTOR inhibitor | CAS 915019-65-7
    $40.00
    NVP-BEZ235 (915019-65-7) is a dual PI3K and mTOR kinase inhibitor.1 It inhibits VEGF-induced proliferation and angiogenesis.2 Reverses lapatinib resistance.3 It induces G1 arrest and reduces cyclin D1...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of PX-866 | PI3-K inhibitor | CAS 502632-66-8
    $58.00
    PX-866 (502632-66-8) inhibits PI-3 Kinase with selectivity for p110α (IC50=0.1 nM). Displays antitumor activity. Irreversible. Cell permeable. References/Citations1) Ihle et al. (2004), Molecular pharmacology and...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Wortmannin | PI3K inhibitor | CAS 19545-26-7
    $35.00
    Wortmannin (19545-26-7) is a potent and selective inhibitor of PI3-kinase which acts via covalent modification of Lys-802.2 Inhibits autophagy in rat hepatocytes.3 Inhibits adipocyte differentiation of 3T3-L1 cells...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of ZSTK474 | PI 3-kinase inhibitor | CAS 475110-96-4
    $48.00
    ZSTK474 (475110-96-4) is a novel Class I phosphatidylinositol 3-kinase (PI3K) inhibitor. ZSTK474 is an ATP-competitive inhibitor of all four Class I PI3K isoforms. However, it inhibits PI3Kδ most potently, with a Ki of...

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