Phospholipases
Showing 1–12 of 34 results
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CD45
(+/-) RK-682 | Tyrosine phosphatase inhibitor
RK-682 (150627-37-5) is a protein tyrosine phosphatase inhibitor (IC50's = 54 7 µM for CD45, 2.0 μM for VHR; did not inhibit cdc25B) originally iso...$75.00 – $295.00 Select options -
Phosphatidylinositols
BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc
BI 2536 (755038-02-9) was originally reported as a potent (IC50’s Plk1 = 0.83nM, Plk2 = 3.5nM and Plk3 = 9.0nM)1 and selective2 Polo-like kinase in...$75.00 – $275.00 Select options -
Bromodomains
Bromosporine | Pan-bromodomain inhibitor
Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1 Bromosporine was able to reactivate HIV-1 replication in different latenc...$80.00 – $275.00 Select options -
Phosphatidylinositols
Candesartan | Angiotensin II antagonist
Candesartan (CAS 139481-59-7) is an angiotensin II receptor I (AT1) antagonist, IC50s=1.12 and 2.86 nM for bovine adrenal cortex and rabbit aorta r...$40.00 – $120.00 Select options -
Phosphatidylinositols
CK-666 | ARP2/3 inhibitor
CK-666 (442633-00-3) is a potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for hum...$65.00 – $240.00 Select options -
Epigenetics
CTPB | p300 HAT activator
CTPB (586976-24-1) is a selective activator of p300 HAT (histone acetyltransferase) selective over PCAF (p300 CPB-associated factor).1,2 Reference...$45.00 – $180.00 Select options -
Cellular Metabolism
Deoxymannojirimycin HCl | Mannosidase inhibitor
Deoxymannojirimycin HCl (CAS 73465-43-7) is a potent and selective inhibitor of α-mannosidase I.1,2 Inhibits the conversion of high mannose to comp...$35.00 – $112.00 Select options -
Bioactive Lipids
Dihydrosphingosine | PKC inhibitor, Sphingosine precursor
Dihydrosphingosine (764-22-7) is a biosynthetic precursor of sphingosine. Inhibitor of protein kinase C1 and phospholipases A2 and D2. Reference...$25.00 – $110.00 Select options -
Phosphatidylinositols
DRB | Transcription inhibitor, CK2 inhibitor
DRB (53-85-0) is a classic inhibitor of transcription by RNA polymerase II. A relatively selective inhibitor of Cdk9 (IC50=3 μM), the kinase of the...$25.00 – $100.00 Select options -
Phosphatidylinositols
DTG | High affinity sigma receptor agonist
DTG (97-39-2) is an agonist of the sigma (σ) receptor1 with roughly equal potency against both subtypes (σ1 and σ2 IC50’s ~ 30nM)2. References/C...$30.00 – $45.00 Select options -
Bioactive Lipids
HTS01037 | FABP inhibitor
HTS01037 (682741-29-3) inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cu...$60.00 – $240.00 Select options -
Phosphoinositides
Idelalisib | Selective PI3Kd Inhibitor
Idelalisib (CAS 870281-82-6) is a potent (IC50 = 2.5nM) and selective (IC50’s: PI3Ka = 820nM, PI3Kb = 565nM, PI3Kg = 89nM) PI3Kd inhibitor.1,2 Usef...$60.00 – $150.00 Select options
