Captopril | Angiotensin-converting enzyme inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 1 gram | $30.00 | ||
| 5 gram | $80.00 |
Captopril (62571-86-2) is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM).1 Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 μM for leukotriene B4> formation and Ki = 60 nM for L-lysine-p-nitroanilide).2 Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.
References/Citations:
1) Cushman et al. (1999), Design of angiotensin converting enzyme inhibitors; Nat.Med., 5 1110
2) Orning et al. (1991), Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril; J.Biol.Chem., 266 16507
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Captopril (62571-86-2) is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM).1 Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 μM for leukotriene B4> formation and Ki = 60 nM for L-lysine-p-nitroanilide).2 Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.
References/Citations:
1) Cushman et al. (1999), Design of angiotensin converting enzyme inhibitors; Nat.Med., 5 1110
2) Orning et al. (1991), Inhibition of leukotriene A4 hydrolase/aminopeptidase by captopril; J.Biol.Chem., 266 16507
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
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