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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of PAC-1 | Procaspase activator | CAS 315183-21-2
    PAC-1 (315183-21-2) is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 µM.1 It is less potent at activating procaspase-7, EC50=4.5 µM. It induces apoptosis in a...

  • Focus Biomolecules cell signaling supplier, chemical structure Q-VD-OPh | Pan-specific caspase inhibitor | CAS 1135695-98-5
    Q-VD-OPh (1135695-98-5) is a potent and highly effective pan-caspase inhibitor with potent antiapoptotic activity which is not toxic to cells.1 Displays protective effects on brain damage and bacterial infection in a murine...

  • Focus Biomolecules supplier, chemical structure of Z-Asp-CH2-DCB | Caspase inhibitor | CAS 153088-73-4
    Z-Asp-CH2-DCB (153088-73-4) is a cell permeable broad spectrum caspase inhibitor. References/Citations1) Dolle et al. (1994) P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of Z-VAD-FMK | Caspase inhibitor | CAS 187389-52-2
    Z-VAD-FMK (187389-52-2), cell-permeable, methyl ester form. Potent, irreversible pan-caspase inhibitor. Inhibits caspase activity and apoptosis induction in a variety of cell types (IC50 = 1.5 μM). Active in vivo...

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