Protein-protein interactions

Showing 1–12 of 16 results

  • Bioactive Lipids

    2-Bromopalmitic acid | Palmitoylation inhibitor

    Rated 0 out of 5
    2-Bromopalmitic acid (18263-25-7) inhibits protein S-palmitoylation.1 Blocks palmitic acid-induced increase in cAMP levels in human primary melanoc...
    $40.00$100.00 Select options

  • Antioxidants

    AI-3 | ARE activator

    Rated 0 out of 5
    AI-3 (882288-28-0) is an activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at C...
    $75.00$300.00 Select options

  • Apoptosis

    CFM-4 | CARP-1 mimetic

    Rated 0 out of 5
    CFM-4 (331458-02-7) is a CARP-1 functional mimetic that interferes with CARP-1 binding to APC-2 (IC50=10-15 μM).1 Enhances CARP-1 expression and in...
    $70.00$280.00 Select options

  • Alzheimers

    Compound 115-7c | HSP70 modulator

    Rated 0 out of 5
    Compound 115-7c (908074-72-6) acts as an artificial co-chaperone for HSP70.1 The activity of compound 115-7c mirrors those of HSP40 stimulating the...
    $90.00$360.00 Select options

  • b-Catenin/CBP

    ICG-001 | Wnt beta-catenin inhibitor

    Rated 0 out of 5
    ICG-001 (847591-62-2) inhibits TCF/β-catenin mediated transcription by specifically blocking β-catenin/CBP interaction References/Citations 1...
    $65.00$250.00 Select options

  • b-Catenin/CBP

    iCRT5 | Beta-catenin inhibitor

    Rated 0 out of 5
    iCRT5 (18623-44-4) is a selective CRT (β-catenin-responsive transcription) inhibitor.1  IC50=18 nM for Wnt responsive STF16 luciferase. Acts via in...
    $57.00$228.00 Select options

  • New Products

    JQ1 (+) | BET Bromodomain inhibitor

    Rated 0 out of 5
    JQ1 (+) (1268524-70-4) is a potent BET bromodomain inhibitor and is the active isomer.   IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2...
    $100.00$400.00 Select options

  • Bromodomains

    JQ1 | Bromodomain inhibitor

    Rated 0 out of 5
    (±) JQ1 (1268524-69-1) is a potent BET bromodomain inhibitor. IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2 (N-terminal (N)), BRD4 (C-...
    $65.00$260.00 Select options

  • Other Protein-protein interactions

    L524-0366 | Fn14 antagonist

    Rated 0 out of 5
    L524-0366 (951612-19-4) is an Fn14 antagonist. Competes with TNF-like weak inducer of apoptosis (TWEAK) C-terminal/extracellular TNF homology domai...
    $65.00$260.00 Select options

  • Cholinergics

    NSC-23766 | Rac1 GTPase inhibitor

    Rated 0 out of 5
    [et_pb_section fb_built="1" _builder_version="3.22" custom_padding="0px||||false|false"][et_pb_row _builder_version="3.25" background_size="initial...
    $67.00$270.00 Select options

  • Cancer

    NSC-66811 | p53/mdm2 inhibitor

    Rated 0 out of 5
    NSC-66811 (6964-62-1) is a novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. NSC-66811 binds to M...
    $100.00$400.00 Select options

  • Cancer

    NSC59984 | p53 activator

    Rated 0 out of 5
    NSC59984 (803647-40-7) is a p53 activator.  Restores wild-type p53 signaling and depletes mutant p53 gain of function. Induces mutant p53 protein d...
    $50.00$150.00 Select options