Pulmonary
Showing 1–12 of 20 results
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Cancer
AG 1478 | EGFR kinase inhibitor
AG-1478 (175478-82-2; base) is a potent and selective inhibitor of the EGFR kinase (IC50 = 3 nM). Inhibits proliferation of a variety human cancer ...$50.00 – $150.00 Select options -
Antioxidants
Ambroxol HCl | Free radical scavenger
Ambroxol HCl (18683-91-5) is a radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveol...$50.00 – $100.00 Select options -
Bioinorganic chemistry
Bleomycin sulfate | Induces double strand DNA breaks
Bleomycin sulfate (9041-93-4) coordinates with metals producing reactive oxygen species which causes oxidative damage to DNA1 and RNA2. Induces dou...$90.00 – $320.00 Select options -
Asthma
Cilostamide | PDE3 inhibitor
Cilostamide (68550-75-4) is a selective inhibitor of phosphodiesterase-3 (PDE3). Displays limited selectivity for PDE3A versus PDE3B (IC50 = 27 and...$60.00 – $240.00 Select options -
Approved Drugs
Fasudil HCl | ROCK inhibitor
Fasudil HCl (105628-07-7) is a Rho-associated kinase inhibitor (IC50 = 1.9 μM and 10.7 μM for Rho-associated kinase II and Rho-associated kinase re...$45.00 – $150.00 Select options -
Bioactive Lipids
Ginkgolide B | PAF receptor antagonist
Ginkgolide B (15291-77-7) is a PAF receptor antagonist (Ki = 1.3 μM)1. Inhibits neutrophil degranulation and superoxide production in vitro1. Inhib...$40.00 – $160.00 Select options -
Asthma
ISO-1 Supplier | CAS 478336-92-4 | Focus Biomolecules
ISO-1 (478336-92-4) is an antagonist of macrophage migration inhibitory factor (MIF, a pro-inflammatory cytokine). Displays anti-inflammatory activ...$105.00 – $420.00 Select options -
Approved Drugs
Minocycline HCl | Neuroprotective; antiapoptotic
Minocycline HCl (13614-98-7) displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. R...$38.00 – $152.00 Select options -
Cellular Stress
Monocrotaline | Induces pulmonary fibrosis
Monocrotaline (315-22-0) is a naturally occurring pyrrolizidine alkaloid used to create an animal model of pulmonary arterial hypertension (PAH). I...$49.00 – $105.00 Select options -
Approved Drugs
Montelukast sodium | Leukotriene antagonist and GPR17 antagonist
Montelukast sodium (151767-02-1) is a potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM).1,2 Displays anti-inflammatory a...$60.00 – $240.00 Select options -
Antioxidants
Pirfenidone | Antifibrotic
Pirfenidone (53179-13-8) is an antifibrotic agent. Prevents lung fibrosis in bleomycin-induced animal models.1 Down-regulates bleomycin-induced ove...$30.00 – $100.00 Select options -
Approved Drugs
Pranlukast | Leukotriene CysLT1 antagonist / GPR17 antagonist
Pranlukast (103177-37-3)is a selective Leukotriene CysLT1 antagonist1 and has been used in the treatment of asthma2. Pranlukast is also an inhibito...$50.00 – $195.00 Select options
