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Pyridone 6 | pan-JAK inhibitor

CAS:

457081-03-7

Catalog Number:

10-5555

Activity:

pan-JAK inhibitor

Chemical Names:

2-(tert-Butyl)-9-fluoro-1Hbenzo[h]imidazo[4,5-f]isoquinolin-7(6H)-one; JAK Inhibitor I

Molecular Weight:

309.34

Molecular Formula:

C₁₈H₁₆FN₃O

Solubility:

Soluble in DMSO (30 mg/ml)

Physical Properties:

Off-white solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

Formoterol hemifumarate | ß2 adrenergic agonist

CAS:

43229-80-7

Catalog Number:

10-5092

Activity:

Potent and selective β2 adrenergic agonist

Chemical Name:

(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl] formamide

Molecular Weight:

402.44

Molecular Formula:

C₁₉H₂₄N₂O₄·1/2C₄H₄O₄

Solubility:

Soluble in DMSO (up to 20 mg/ml)

Physical Properties:

White to off-white solid

Purity:

99% HPLC
NMR (Conforms)

Storage Temperature:

Room temperature

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

N6022 | S-Nitrosoglutathione reductase inhibitor

CAS:

1208315-24-5

Catalog Number:

10-4103

Activity:

S-Nitrosoglutathione reductase inhibitor

Chemical Name:

3-(5-(4-(1H-Imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid

Molecular Weight:

414.46

Molecular Formula:

C₂₄H₂₂N₄O₃

Solubility:

Soluble in DMSO (up to at least 25 mg/ml).

Physical Properties:

White solid

Purity:

98% by HPLC

NMR (Conforms)

Storage Temperature:

-20° C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Shipping Code:

Fibrosis

Cycloastragenol | Telomerase activator/Senolytic agent

Cycloastragenol (84605-18-5) is a novel naturally occurring terpenoid found in Astragalus which was shown to be a telomerase activator. In CD8+ T lymphocytes from HIV-infected donors

Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor

Nintedanib (656247-17-5) is a potent inhibitor of VEGFR, PDGFR, FGFR (IC50 = 13-34 nM for VEGFR, 59-65 nM for PDGFR and 37-108 nM for FGFR subtypes).1 Also

IM156 | AMPK activator/Mitochondrial protein complex I inhibitor

CAS:

1422365-93-2

Catalog Number:

10-4657

Activity:

AMPK activator/Mitochondrial complex I inhibitor

Chemical Names:

N’-[N’-[4-(Trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboxamidine

Alternate Name:

HL156A

Molecular Weight:

315.30

Molecular Formula:

C₁₃H₁₆F₃N₅O

Solubility:

Soluble in DMSO (25 mg/ml)

Physical Properties:

White solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

Other Pulmonary

Formoterol hemifumarate | ß2 adrenergic agonist

CAS:

43229-80-7

Catalog Number:

10-5092

Activity:

Potent and selective β2 adrenergic agonist

Chemical Name:

(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl] formamide

Molecular Weight:

402.44

Molecular Formula:

C₁₉H₂₄N₂O₄·1/2C₄H₄O₄

Solubility:

Soluble in DMSO (up to 20 mg/ml)

Physical Properties:

White to off-white solid

Purity:

99% HPLC
NMR (Conforms)

Storage Temperature:

Room temperature

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

VGX-1027 | Immunomodulator; Cytokine release inhibitor

CAS:

6501-72-0

Catalog Number:

10-3409

Activity:

Immunomodulator; Cytokine release inhibitor

Chemical Name:

4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid

Alternate Name:

GIT 27

Molecular Weight:

205.21

Molecular Formula:

C₁₁H₁₁NO₃

Solubility:

Soluble in DMSO (up to 30 mg/ml).

Physical Properties:

White solid

Purity:

98% by HPLC

NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:

Sildenafil citrate | PDE5 inhibitor

CAS:

171599-83-0

Catalog Number:

10-1221

Activity:

PDE5 inhibitor

Chemical Names:

1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate; UK-92480

Molecular Weight:

666.70

Molecular Formula:

C₂₂H₃₀N₆O₄S • C₆H₈O₇

Solubility:

Soluble in DMSO (up to 60 mg/ml)

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

Asthma

Pyridone 6 | pan-JAK inhibitor

Formoterol hemifumarate | ß2 adrenergic agonist

N6022 | S-Nitrosoglutathione reductase inhibitor

Fibrosis

Cycloastragenol | Telomerase activator/Senolytic agent

Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor

IM156 | AMPK activator/Mitochondrial protein complex I inhibitor

Other Pulmonary

Formoterol hemifumarate | ß2 adrenergic agonist

VGX-1027 | Immunomodulator; Cytokine release inhibitor

Sildenafil citrate | PDE5 inhibitor

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Pulmonary

Asthma

Fibrosis

Other Pulmonary

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21