Asthma
Showing all 9 results
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Asthma
Cilostamide | PDE3 inhibitor
Cilostamide (68550-75-4) is a selective inhibitor of phosphodiesterase-3 (PDE3). Displays limited selectivity for PDE3A versus PDE3B (IC50 = 27 and...$60.00 – $240.00 Select options -
Adrenergic
Formoterol hemifumarate | ß2 adrenergic agonist
Formoterol hemifumarate (43229-80-7) is a potent, long-acting agonist specific to β2 (Ki = 7.6 nM), but not β1 (Ki > 2.6 µM), adrenergic recepto...$68.00 – $200.00 Select options -
Asthma
ISO-1 | MIF antagonist
ISO-1 (478336-92-4) is an antagonist of macrophage migration inhibitory factor (MIF, a pro-inflammatory cytokine). Displays anti-inflammatory activ...$105.00 – $420.00 Select options -
Approved Drugs
Montelukast sodium | Leukotriene antagonist and GPR17 antagonist
Montelukast sodium (151767-02-1) is a potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM).1,2 Displays anti-inflammatory a...$60.00 – $240.00 Select options -
Approved Drugs
Pranlukast | Leukotriene CysLT1 antagonist / GPR17 antagonist
Pranlukast (103177-37-3)is a selective Leukotriene CysLT1 antagonist1 and has been used in the treatment of asthma2. Pranlukast is also an inhibito...$50.00 – $195.00 Select options -
New Products
Pyridone 6 | pan-JAK inhibitor
Pyridone 6 (457081-03-7) is a potent, ATP-competitive pan-JAK inhibitor. Inhibits 1, 2 and 3 (IC50=1, 5 and 15 nM respectively) as well as JAK fami...$60.00 – $116.00 Select options -
Approved Drugs
Suplatast tosilate | Immunomodulator
Suplatast tosilate (94055-79-2) is a potent immunoregulator that suppresses IgE production.1 Suppresses innate immunity by down-regulating TLR2, TL...$55.00 – $220.00 Select options -
Approved Drugs
Zafirlukast | HSP70 inhibitor and leukotriene antagonist
Zafirlukast (107753-78-6) is a competitive and selective leukotriene receptor antagonist.1 Also inhibits calcium ionophore induced production of le...$28.00 – $55.00 Select options -
Asthma
Zileuton | 5-LO inhibitor
Zileuton (111406-87-2) is a reversible inhibitor (IC50 = 500nM RBL-1 cells, 300nM rat PMNL cells) of 5-Lipoxygenase (5-LO).1 It also inhibited leuk...$30.00 – $120.00 Select options
