Fibrosis Archives | Focus Biomolecules

AG 1478 | EGFR kinase inhibitor

CAS:

175178-82-2

Catalog Number:

10-2117

Activity:

EGFR kinase inhibitor

Chemical Name:

N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine, free base

Molecular Weight:

315.76

Molecular Formula:

C₁₆H₁₄ClN₃O₂

Solubility:

Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming).

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $50.00
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BI 749327 | Selective TRPC6 blocker

CAS:

2361241-23-6

Catalog Number:

10-4318

Activity:

Selective TRPC6 blocker

Chemical Names:

[4-(6-Aminopyridazin-3-yl)piperidin-1-yl]-[4-[4-(trifluoromethyl)phenoxy]phenyl]methanone

Molecular Weight:

442.44

Molecular Formula:

C₂₃H₂₁F₃N₄O₂

Solubility:

Soluble in DMSO (25 mg/ml)

Physical Properties:

White solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $80.00
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Bleomycin sulfate | Induces double strand DNA breaks

CAS:

9041-93-4

Catalog Number:

10-2623

Activity:

Fibrosis-inducing agent

Source:

From Streptomyces verticillus

Molecular Weight:

1512.62

Molecular Formula:

C₅₅H₈₅N₁₇O₂₅S₄

Solubility:

Soluble in Water (up to 20 mg/ml)

Physical Properties:

White or off-white solid

Purity:

Contains a mixture of A₂ (~70%) and B₂ (~30%) forms

95% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
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Cycloastragenol | Telomerase activator/Senolytic agent

Cycloastragenol (84605-18-5) is a novel naturally occurring terpenoid found in Astragalus which was shown to be a telomerase activator. In CD8+ T lymphocytes from HIV-infected donors […]

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Fasudil HCl | ROCK inhibitor

CAS:

105628-07-7

Catalog Number:

10-2137

Activity:

ROCK inhibitor

Alternate Names:

HA-1077

Chemical Name:

1-(5-Isoquinolinesulfonyl)homopiperazine HCl

Molecular Weight:

327.84

Molecular Formula:

C₁₄H₁₇N₃O₂S HCl

Solubility:

Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

RT

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $52.00
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