my account
Login
  Loading... Please wait...

Notch

Sort by
  • Focus Biomolecules cell signaling reagent supplier, chemical structure of DAPT | gamma-secretase inhibitor | CAS 208255-80-5
    $60.00
    DAPT (208255-80-5)is an inhibitor of γ-secretase (IC50 in human primary neurons = 115 nM for total Aβ or 200 nM for Aβ42 specifically)1. Oral administration of DAPT has been shown to reduce levels of Aβ...

  • Focus Biomolecules cell signaling reagent supplier, chemical structure of FLI-06 | Notch pathway inhibitor | CAS 313967-18-9
    $80.00
    FLI-06 (313967-18-9) was discovered in a screen designed to monitor the trafficking and processing of a ligand-independent Notch-enhanced GFP reporter. It was found to disrupt the Golgi apparatus in a manner distinct from...

  • IMR-1 | Notch transcriptional activation inhibitor
    $60.00
    Inhibitor of Mastermind Recruitment-1 (IMR-1, 310456-65-6) disrupts the recruitment of Mastermind-like 1 to the Notch transcriptional activation complex (NTC) on chromatin, which attenuates Notch target gene transcription1...

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus