Stem Cells
Dedifferentiation Differentiation Generation Proliferation Self renewal/maintenance Other Stem cells
Showing 1–12 of 101 results
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Dedifferentiation
(±) Tranylcypromine hemisulfate | Demethylase inhibitor
Tranylcypromine (13492-01-8) is an irreversible and non-selective monoamine oxidase inhibitor.1,2 It has been shown to inhibit the histone demethyl...$40.00 – $150.00 Select options -
Cardiovascular
1-EBIO | K+ channel activator; Promotes cardiomyocyte differentiation
1-EBIO (10045-45-1) is a direct activator of small-conductance Ca2+-activated K+ channels (SK) which dose-dependently relaxes rat mesenteric vessel...$40.00 – $148.00 Select options -
Adipogenesis
20(S)-Hydroxycholesterol | Smoothened activator
20(S)-Hydroxycholesterol (516-72-3) is an endogenous ligand for the LXR receptor.1 It has anti-adipogenic and pro-osteogenic effects in mesenchymal...$40.00 – $90.00 Select options -
Cholesterol
24(S),25-Epoxycholesterol | LXR agonist
24(S),25-Epoxycholesterol (77058-74-3) is a cholesterol metabolite that acts as an endogenous agonist for nuclear receptor LXR.1 Controls cellular ...$100.00 – $400.00 Select options -
Cancer
5-Azacytidine | DNA hypomethylation agent
5-Azacytidine (320-67-2) is specific inhibitor of DNA methyltransferase.1 Incorporates into DNA and covalently reacts with and inhibits DNA methylt...$20.00 – $80.00 Select options -
Cardiovascular
6BIO | GSK-3 inhibitor
6BIO (667463-62-9) is a potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM.1 The first pharmacological agent shown to m...$65.00 – $260.00 Select options -
ALK
A 83-01 | ALK inhibitor
A 83-01 (909910-43-6) is a potent and selective ALK4, 5 and 7 inhibitor.1,2 IC50 = 45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad...$50.00 – $180.00 Select options -
New Products
A939572 | SCD1 inhibitor
A939572 (1032229-33-6) is a potent stearoyl-CoA desaturase 1 (SCD1) inhibitor (IC50s = mouse: <4 nM, human: 37 nM).1 Active in various cancer mo...$65.00 – $225.00 Select options -
Cardioprotection
AA147 | ATF6 activator
AA147 (393121-74-9) is a preferential activator of the ER stress sensing protein ATF6.1 It was able to selectively reduce secretion and extracellul...$70.00 – $275.00 Select options -
Differentiation
AM-580 | RARα agonist
AM-580 (102121-60-8) is a retinoic acid analog acting as a RARα agonist (Kd = 8 nM).1 Induces or blocks differentiation depending on cell type and ...$70.00 – $200.00 Select options -
Cardiovascular
AS-8351 | KDM5B histone demethylase inhibitor
AS-8351 (796-42-9) has been used in a cocktail of nine small molecules used to efficiently induce cardiac reprogramming of human fibroblasts.1 It i...$50.00 – $200.00 Select options -
Calcium
BAY K8644 | L-type calcium channel activator
BAY K8644 (71145-03-4) is an L-type Ca2+-channel activator with positive inotropic and vasoconstrictive effects.1-4 References/Citations: 1) ...$65.00 – $250.00 Select options
