Generation
Showing 1–12 of 17 results
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Calcium
BAY K8644 | L-type calcium channel activator
BAY K8644 (71145-03-4) is an L-type Ca2+-channel activator with positive inotropic and vasoconstrictive effects.1-4 References/Citations: 1) ...$65.00 – $250.00 Select options -
Epigenetics
BIX-01294 | Histone Methyltransferase inhibitor
BIX-01294 (935693-62-2) is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 μM) as well as GLP HMTase (IC50 = 38 μM) l...$60.00 – $240.00 Select options -
Adipogenesis
CHIR-99021 | GSK3ß inhibitor
CHIR-99021 (252917-06-9) is a potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM).1 Induces...$60.00 – $170.00 Select options -
Adipogenesis
Ciglitazone | PPARgamma agonist
Ciglitazone (74772-77-3) is a PPARγ agonist (EC50=3 μM). Stimulates adipogenesis in human mesenchymal stem cells. Ciglitazone inhibits HUVEC differ...$80.00 – $320.00 Select options -
Angiogenesis
DZNep | Methyltransferase inhibitor
DZNep (102052-95-9) is a potent histone methyltransferase inhibitor which decreases global histone methylation.1 Inhibits trimethylation of H3K27 a...$142.00 – $550.00 Select options -
New Products
Emricasan | pan-Caspase inhibitor
Emricasan (254750-02-2) is a liver-targeted antiapoptotic pan-caspase inhibitor.1,2 It has been investigated as a hepatoprotective agent in the tre...$80.00 – $310.00 Select options -
Adenylate cyclase activators
Forskolin | Adenylate cyclase activator
Forskolin (66575-29-9) is a widely used adenylate cyclase activator.1 Forskolin also is a positive inotropic agent, vasodilator and induces platele...$60.00 – $130.00 Select options -
New Products
GSK126 | EZH2 methyltransferase inhibitor
GSK126 (1346574-57-9) is a potent, selective, S-adenosyl-methionine-competitive inhibitor of EZH2 methyltransferase, Ki=0.5-3 nM, >150-fold sele...$70.00 – $325.00 Select options -
New Products
HA-100·2HCl | Multi-kinase inhibitor
HA-100·2HCl (85568-24-6) inhibits the following kinases PKG (IC50=4 mM), PKA (IC50=8 mM), PKC (IC50=12 mM).1 Increases human fibroblast reprogramm...$50.00 – $200.00 Select options -
Arthritis
Kenpaullone | GSK-3ß/CDK/KLF4 inhibitor
Kenpaullone (142273-20-9) inhibits GSK-3β (IC50=0.23 µM) as well as several cyclin-dependent kinases (CDKs), IC50=0.4, 0.68 and 0.85 µM for cdk1, c...$80.00 – $240.00 Select options -
Generation
LM11A-31 | p75NTR ligand / Promotes neurogenesis
LM11A-31 (1243259-19-9) is a nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-respon...$48.00 – $192.00 Select options -
Differentiation
Neurodazine | Induces stem cell neuronal differentiation
Neurodazine (937807-66-4) was able to induce neurogenesis of non-pluripotent myoblasts and cells derived from mature, human skeletal muscle (using ...$70.00 – $250.00 Select options
