Stem Cells
Dedifferentiation Differentiation Generation Proliferation Self renewal/maintenance Other Stem cells
Showing 61–72 of 98 results
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Angiogenesis
PD173074 | FGFR inhibitor
PD173074 (219580-11-7) is an inhibitor of FGFR tyrosine kinase, and to a lesser extent VEGFR1 (IC50 values are 5 nM, 22.5 nM and 100 nM for FGFR1, ...$40.00 – $150.00 Select options -
New Products
PFI-3 | Selective Bromodomain family VIII inhibitor
PFI-3 (1819363-80-8) is a selective inhibitor of family VIII bromodomains PB1(5), SMARCA2, and SMARCA4.1 It showed complete selectivity over all no...$59.00 – $215.00 Select options -
Apoptosis
Pifithrin α | p53 inhibitor
Pifithrin α (63208-82-2) is a reversible inhibitor of p53-mediated transcription and p53-dependent apoptosis. Enhances survival after genotoxic str...$50.00 – $195.00 Select options -
Approved Drugs
Plerixafor | CXCR4 antagonist
Plerixafor (155148-31-5) is a highly selective CXCR4 antagonist (IC50 = 20-130 nM).1,2 Originally investigated as an HIV replication inhibitor.3 Pl...$50.00 – $175.00 Select options -
Bioactive Lipids
Prostaglandin E2 | Prostaglandin E (EP) receptor agonist
Prostaglandin E2 (363-24-6; PGE2) is an endogenous prostaglandin derived from the action of cyclooxygenase on arachidonic acid. PGE2 has diverse bi...$25.00 – $125.00 Select options -
New Products
PTC-209 | BMI-1 inhibitor
PTC-209 (315704-66-6) is an inhibitor of BMI-1 (IC50 = 500 nM), part of the polycomb repressive complex 1 (PCR1).1 It inhibited endogenous BMI-1 e...$65.00 – $240.00 Select options -
Dedifferentiation
Purmorphamine | Smoothened activator
Purmorphamine (CAS 483367-10-8) induces osteogenesis in multipotent mesenchymal progenitor cells via activation of hedgehog signaling.1,2 Activati...$75.00 – $250.00 Select options -
New Products
Pyridone 6 | pan-JAK inhibitor
Pyridone 6 (457081-03-7) is a potent, ATP-competitive pan-JAK inhibitor. Inhibits 1, 2 and 3 (IC50=1, 5 and 15 nM respectively) as well as JAK fami...$60.00 – $116.00 Select options -
ALK
RepSox | TGFß type I / ALK5 inhibitor
RepSox (446859-33-2) is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-β cellular assay = 23 nM) inhibitor of the TGF-β type I receptor (ALK5).1 RepSox...$65.00 – $250.00 Select options -
Approved Drugs
Retinoic acid | Retinoid RAR agonist
all-trans-Retinoic acid (302-79-4) a metabolite of Vitamin A, is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic...$22.00 – $45.00 Select options