NF-kB
Showing 1–12 of 27 results
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Cancer
Anacardic Acid | HAT inhibitor
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50...$35.00 – $140.00 Select options -
Antivirals
Andrographolide | Induces mitochondrial-mediated apoptosis
Andrographolide (5508-58-7) is the major bioactive component of the medicinal plant Andrographis paniculate. Demonstrates anti-inflammatory anti-ap...$34.00 – $136.00 Select options -
Antioxidants
CAPE | Inhibits NFkB activation
CAPE (104594-70-9) is an antioxidant that inhibits NFκB activation and the growth of transformed cells. CAPE inhibits lipid peroxidation and displa...$30.00 – $54.00 Select options -
Cellular Stress
Cardamonin | NFkB inhibitor
Cardamonin (19309-14-9) inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear t...$60.00 – $240.00 Select options -
New Products
CDDO-Me | Nrf2 activator
CDDO-Me (218600-53-4) is a potent activator of Nrf2 target transcription via interaction with thiol groups of Keap1, an Nrf2 partner, in phase 2 re...$60.00 – $198.00 Select options -
Antioxidants
Celastrol | Proteasome inhibitor
Celastrol (34157-83-0) displays potent antioxidant and anti-inflammatory activity. Inhibits NFkB (IC50=270 nM). It induces heat shock response and...$50.00 – $200.00 Select options -
New Products
Chromomycin A3 | DNA Stain
Chromomycin A3 (7059-24-7) is a DNA-binding agent specific for GC-rich sequences1 which may be used as a DNA stain2. Inhibits neuronal apoptosis in...$52.00 – $150.00 Select options -
GPCRs
Diphenyleneiodonium chloride | Flavoprotein inhibitor
Diphenyleneiodonium chloride (4673-26-1) is an irreversible inhibitor of iNOS and eNOS (IC50s=50 and 100 nM respectively).1 Binds to and inhibits t...$55.00 – $220.00 Select options -
Cancer
DMAPT | NFkB inhibitor
DMAPT (870677-05-7) is a water soluble analog of the natural plant product parthenolide (Cat.# 10-2096) which suppresses in vivo tumor growth of tw...$50.00 – $175.00 Select options -
Cellular Stress
Helenalin | NFkB inhibitor
Helenalin (6754-13-8) is a novel sesquiterpene lactone which inhibits NFκB1 and displays potent anti-inflammatory activity2. It suppresses essentia...$238.00 Select options -
New Products
Homoharringtonine | Protein synthesis inhibitor
Homoharringtonine (26833-87-3) is a plant alkaloid, originally isolated from the Hainan plum yew, that binds to the large ribosomal subunit A-site,...$65.00 – $220.00 Select options -
New Products
Isohelenin | NFkB inhibitor
Isohelenin (470-17-7) is a sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent...$50.00 – $180.00 Select options
