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  • Focus Biomolecules cell signaling reagent supplier, chemical structure of BI-6015 | HNF4a inhibitor | CAS 93987-29-2
    BI-6015 (93987-29-2) is a hepatocyte nuclear factor 4α (HNF4α) antagonist. HNF4α is a central regulator of gene expression in cell types that play a central role in metabolic homeostasis.1 BI-6015 binds to...

  • Focus Biomolecules supplier, chemical structure of Fatostatin | SREBP activation inhibitor | CAS 125256-00-0
    Fatostatin (125256-00-0) blocks adipogenesis by inhibiting the activation of SREBP. Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Fatostatin prevents increases in body weight,...

  • FQI1 | LSF inhibitor
    FQI1 (599151-35-6) is an inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 μM). Rapidly induces apoptosis in an aggressive hepatocellular...

  • Focus Biomolecules cell signaling supplier, chemical structure of Mithramycin A | Transcription inhibitor | CAS 18378-89-7
    Mithramycin A (18378-89-7) inhibits DNA methyl transferase.1 A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibiting their expression.2...

  • Focus Biomolecules supplier, chemical structure of Stauprimide | Primes stem cells for differentiation | CAS 154589-96-5
    Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation. Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby...

  • Focus Biomolecules supplier, chemical structure of Thiostrepton | Antibiotic and FOXM1 inhibitor | CAS 1393-48-2
    Thiostrepton (1393-48-2) is a novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as...

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